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What we can know about biology before the last universal common ancestor is limited—and we should be circumspect in filling in the gaps.

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Acute bouts of diarrhea could have lasting effects on the microbiota and host immune system activation, a mouse study suggests.

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image: This Flu Season Killed 172 Kids

This Flu Season Killed 172 Kids

By Sukanya Charuchandra | June 11, 2018

Vaccination reduced the risk of death by two-thirds for children with no other health problems.  

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The receptors, found in so-called elite controllers who don’t need medications to keep the virus in check, suggest a new path toward immunotherapy.

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image: Dogs in Southern China Host Several Strains of Flu

Dogs in Southern China Host Several Strains of Flu

By Sukanya Charuchandra | June 6, 2018

They may be a prospective source for an influenza pandemic, researchers warn.  

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The results suggest the virus could severely alter brain development in infants infected after birth, but blocking a signaling protein early on might ease certain symptoms.

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Compared with their urban counterparts, babies and toddlers in rural Nigeria have gut microbiota that more closely resembles that of adults in their community.

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image: New Insights to Improve CAR T Cells’ Safety

New Insights to Improve CAR T Cells’ Safety

By Vicki Brower | June 5, 2018

Drugs approved to treat rheumatoid arthritis block cytokines, the molecules responsible for severe side effects from the immunotherapy, and reduce symptoms in mice.

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image: A T-Cell Tweak Combats Advanced Breast Cancer

A T-Cell Tweak Combats Advanced Breast Cancer

By Ashley Yeager | June 5, 2018

The immunotherapy eliminated a woman’s metastatic lesions and kept her disease-free for two years.

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image: Immunotherapy Drug Shows Promise for Melanoma, Lung Cancer

Immunotherapy Drug Shows Promise for Melanoma, Lung Cancer

By Sukanya Charuchandra | June 4, 2018

Merck’s Keytruda extended the lives of lung cancer patients by several months and appeared to stop the progression of advanced melanoma.  

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