viral vectors, genetics & genomics

The FDA pauses the research program on a lentivirus-based treatment for a rare neurological condition after a patient developed a bone marrow disorder that could presage leukemia.

Clinical trials were halted after the treatment’s vector that ferries in the healthy genetic sequence was identified in the genome of a patient’s cancer cells.

Phages interact with bacteria and eukaryotic cells in ways that researchers suspect influence mammalian health.

Adeno-associated viral vectors can deliver gene therapies, but AAV-neutralizing antibodies might prevent the medicines from working.

Researchers boosted levels of the dystrophin protein to nearly normal levels in a canine model of the disease.

A Brazilian town will ramp up the release of insects engineered to shrink mosquito populations.

In a mouse model of a rare disease, scientists have figured out how to reduce the elevated cancer risk tied to a gene therapy treatment.

After 20 years of high-profile failure, gene therapy is finally well on its way to clinical approval.