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tag neurodegenerative diseases culture neuroscience disease medicine developmental biology

Cropped view of senior man playing with puzzles
A Rare Genetic Mutation Protects Against Alzheimer's Disease
Hannah Thomasy, PhD, Drug Discovery News | Sep 17, 2023 | 4 min read
Data from a highly resilient individual guided researchers to new potential therapeutic targets.
On the left is a normally developing mouse embryo, on the right is a slightly larger mouse embryo that also contains horse cells that glow green.
Chimera research opens new doors to understanding and treating disease
Hannah Thomasy, PhD, Drug Discovery News | Aug 9, 2023 | 10 min read
Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Exploring the Past, Present, and Future of Brain Organoids 
Niki Spahich, PhD | Feb 18, 2024 | 5 min read
Paola Arlotta seeks to understand the complex symphony of brain development in vitro by using organoid models.
A collection of images from previous neuroscience articles, including those of an octopus in a chamber, artistic renditions of a brain, brain scans, and an image of neural connections in vitro.
Our Favorite Neuroscience Stories of 2022
Dan Robitzski | Dec 28, 2022 | 4 min read
This year, neuroscience researchers made important discoveries related to how neurodegeneration attacks the human brain, hooked cultured neurons up to machinery to teach them to play a video game, and more.
bace1 alzheimer's disease gga3 axon neuron
Alzheimer’s-Linked Mutation Causes Blockages in Neurons
Ian Le Guillou | Nov 20, 2020 | 3 min read
The variant causes a buildup of BACE1 protein in axons in cultured neurons and mice. Researchers say it might be time to rethink failed trials that inhibit BACE1 to treat the neurodegenerative disease.
Developmental Neuroscience Blossoming In The 1990s
Neeraja Sankaran | Nov 13, 1994 | 5 min read
Society for Neuroscience 11 Dupont Circle, N.W.Suite 500 Washington, D.C. 20036 Phone: (202) 462-6688 Nancy Beang, executive director Carla Shatz, president 23,000 members International Society for Developmental Neuroscience University of Texas Medical Branch Galveston, Texas 77550-0652 Phone: (409) 772-3667 Fax: (409) 772-8028 E-mail: regino@beach.utmb.edu Arne Schousboe, president Regino Perez-Polo, secretary-general 1,000 m
Developmental Neuroscience Blossoming In The 1990s
Neeraja Sankaran | Nov 13, 1994 | 5 min read
Society for Neuroscience 11 Dupont Circle, N.W.Suite 500 Washington, D.C. 20036 Phone: (202) 462-6688 Nancy Beang, executive director Carla Shatz, president 23,000 members International Society for Developmental Neuroscience University of Texas Medical Branch Galveston, Texas 77550-0652 Phone: (409) 772-3667 Fax: (409) 772-8028 E-mail: regino@beach.utmb.edu Arne Schousboe, president Regino Perez-Polo, secretary-general 1,000 m
Can Viruses in the Genome Cause Disease?
Katarina Zimmer | Jan 1, 2019 | 10+ min read
Clinical trials that target human endogenous retroviruses to treat multiple sclerosis, ALS, and other ailments are underway, but many questions remain about how these sequences may disrupt our biology.
a false color transmission electron microscope image of a neuronal cell body, with lysosomes colored dark green
Scientists Uncover Major Pathway Cells Use to Mend Leaky Lysosomes
Holly Barker, PhD | Oct 6, 2022 | 3 min read
Damaged lysosomes are repaired by a lipid-based signaling pathway dubbed PITT that could be targeted to treat neurodegenerative disease, its discoverers say.

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