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The AIDS Research Evaluators
Lynn Gambale | Jul 9, 1995 | 6 min read
Chairman: Arnold Levine, chairman, department of molecular biology, Princeton University Barry Bloom, Weinstock Professor and Howard Hughes Medical Institute (HHMI) investigator, department of microbiology and immunology, Albert Einstein College of Medicine, New York Rebecca Buckley, professor of pediatrics and immunology, Duke University Medical Center Charles Carpenter, chairman, Office of AIDS Research Advisory Committee; professor of medicine,Brown University School of Medicine Don
The Role of Mom’s Microbes During Pregnancy
Carolyn A. Thomson and Kathy D. McCoy | Aug 1, 2021 | 10+ min read
Bacteria in the gut influence the production of antibodies and themselves secrete metabolites. In a pregnant woman, these compounds may influence immune development of her fetus.
Distinguishing Th1 and Th2 Cells
Jeffrey Perkel | May 13, 2001 | 10+ min read
Reagents That Distinguish Th1 and Th2 cells Courtesy of R&D SystemsSchematic representation of cytokines influencing the development of antigen-activated naive CD4+ T cells into Th1 and Th2 cells. Editor's note: Although individual techniques are associated with specific researchers in this article, it should be noted that these investigators commonly use several different techniques to analyze T lymphocyte populations. The human body is constantly under siege. It must defend itself fr
Uses Of Enzyme Immunoassays Growing In Laboratories And Clinics
Holly Ahern | Feb 6, 1994 | 9 min read
Life Technologies P.O. Box 6009 8451 Helgerman Court Gaithersburg, Md. 20884 (301) 840-4150 Fax: (800) 331-2286 MGM Instruments Inc. 925 Sherman Ave. Hamden, Conn. 06514 (203) 248-4008 Fax: (203) 288-2621 Nordic Immunological Labs Drawer 2517 Capo Beach, Calif. 92624 (714) 498-4467 Fax: (714) 361-0138 Organon Teknika/ Biotechnology Research Institute 1330 Piccard Dr. Rockville, Md. 20850-4396 (800) 354-0809 Fax: (301) 840-2161
Flow Cytometry: It's Not Just For Immunologists Anymore
James Kling | Jun 22, 1997 | 9 min read
A low-profile child of the '60s, flow cytometry didn't capture the imagination of most researchers until the early 1980s. The decade saw the birth of the AIDS epidemic, and as attention focused on HIV, researchers needed a method to accurately and reproducibly characterize immune cells. Flow cytometry was suddenly thrust into the spotlight. COMPLETE KITS: Bio-Rad’s KINESIS reagent kits for flow cytometry assays A flow cytometer shines one or more lasers on a sample of cells in suspension
One Step Beyond: Going Beyond Genomics With Proteomics And Two-Dimensional Gel Technology
Laura Defrancesco | Jan 3, 1999 | 10+ min read
Proteomes and 2D Gel Apparatus Providers Big science has moved on to proteins. With the new brand of science termed proteomics--named by the Australians Marc Wilkins and Keith Williams to mean the "set of PROTEins encoded by the genOME"--the push is on around the globe to produce a complete description of a cell/tissue/organism in terms of the proteins produced. The challenge is all the greater because the expressed protein pattern changes with time and environment--responding to developmenta
Epigenetics: Genome, Meet Your Environment
Leslie Pray | Jul 4, 2004 | 10+ min read
©Mehau Kulyk/Photo Researchers, IncToward the end of World War II, a German-imposed food embargo in western Holland – a densely populated area already suffering from scarce food supplies, ruined agricultural lands, and the onset of an unusually harsh winter – led to the death by starvation of some 30,000 people. Detailed birth records collected during that so-called Dutch Hunger Winter have provided scientists with useful data for analyzing the long-term health effects of prenat
Notebook
Ricki Lewis | Apr 11, 1999 | 7 min read
Peanuts may be losing their bite PEANUT ALLERGY VACCINE Peanuts are more than just an annoyance on airplanes--for a few dozen people each year, they cause deadly anaphylactic shock. The only protection is knowledge of one's allergy and avoidance of the offending food. But most peanut-associated allergic deaths occur from peanut extracts added to prepared foods--additives that sometimes remain unlisted on labels. A peanut allergy vaccine could prevent such deaths. Kam Leong, a professor of biom
Hughes Medical Institute Spreads Its Riches Far And Wide
The Scientist Staff | Jul 23, 1989 | 6 min read
“I didn’t need to think about the offer very long,” Tjian says with a laugh, recalling his initial shock. HHMI was offering to bankroll Tjian’s research on DNA transcription for a minimum of seven years, and possibly for the rest of his career. And he wasn’t the only one. As the nation’s largest private sponsor of biomedical research, the institute spent about $200 million last year supporting senior investigators like Tjian. After becoming a Hughes Instit
Articles Alert
Simon Silver | Jun 24, 1990 | 7 min read
The Scientist has asked a group of experts to comment periodically upon recent articles that they have found noteworthy. Their selections, presented herein every issue, are neither endorsements of content nor the result of systematic searching. Rather, the list represents personal choices of articles the columnists believe the scientific community as a whole may also find interesting. Reprints of any articles cited here may be ordered through The Genuine Article, 3501 Market St., Philadelphia,

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