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A single receptor on natural killer cells recognizes an amino acid sequence conserved across Zika, dengue, and related pathogens.

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image: How Poison Frogs Avoid Poisoning Themselves

How Poison Frogs Avoid Poisoning Themselves

By | September 21, 2017

Amphibians resist their own chemical defenses with amino acid modifications in the sequence for a target receptor.

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image: How Immune Receptors Got into Mouse Noses

How Immune Receptors Got into Mouse Noses

By | September 1, 2017

A study traces proteins’ evolution from the immune to the olfactory system.

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image: Chemogenetics Doesn’t Work Like Many Thought

Chemogenetics Doesn’t Work Like Many Thought

By | August 4, 2017

A study finds the so-called DREADD method of manipulating neurons using a drug called CNO actually works via clozapine.

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image: Endocannabinoids in the Groove

Endocannabinoids in the Groove

By | July 17, 2017

The system responsible for the buzz humans get from marijuana plays a passel of physiological roles outside the brain.

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The cell-surface receptor, SIRP-alpha, initiates the innate immune response in hosts.  

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image: Deep Pocket Exploration

Deep Pocket Exploration

By | February 1, 2017

A modification to traditional docking software enables the examination of a ligand’s passage into its receptor.

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image: Infographic: Modeling Molecules’ Receptor Binding

Infographic: Modeling Molecules’ Receptor Binding

By | February 1, 2017

A software upgrade follows ligands step-wise into their binding sites on receptors.

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image: What Sensory Receptors Do Outside of Sense Organs

What Sensory Receptors Do Outside of Sense Organs

By | September 1, 2016

Odor, taste, and light receptors are present in many different parts of the body, and they have surprisingly diverse functions.

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image: Hydropowered Pollen

Hydropowered Pollen

By | February 1, 2016

A tension-sensing ion channel regulates hydration and germination in pollen.

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