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The receptors, found in so-called elite controllers who don’t need medications to keep the virus in check, suggest a new path toward immunotherapy.

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image: Genetic Adaptation to Cold Brought Migraines With It

Genetic Adaptation to Cold Brought Migraines With It

By Viviane Callier | May 3, 2018

Humans living in higher latitudes tend to have a variant of a gene involved in sensing cold temperatures, but it comes with a cost.  

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A single receptor on natural killer cells recognizes an amino acid sequence conserved across Zika, dengue, and related pathogens.

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image: How Poison Frogs Avoid Poisoning Themselves

How Poison Frogs Avoid Poisoning Themselves

By Abby Olena | September 21, 2017

Amphibians resist their own chemical defenses with amino acid modifications in the sequence for a target receptor.

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image: How Immune Receptors Got into Mouse Noses

How Immune Receptors Got into Mouse Noses

By Shawna Williams | September 1, 2017

A study traces proteins’ evolution from the immune to the olfactory system.

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image: Chemogenetics Doesn’t Work Like Many Thought

Chemogenetics Doesn’t Work Like Many Thought

By Kerry Grens | August 4, 2017

A study finds the so-called DREADD method of manipulating neurons using a drug called CNO actually works via clozapine.

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image: Endocannabinoids in the Groove

Endocannabinoids in the Groove

By Megan Scudellari | July 17, 2017

The system responsible for the buzz humans get from marijuana plays a passel of physiological roles outside the brain.

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The cell-surface receptor, SIRP-alpha, initiates the innate immune response in hosts.  

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image: Deep Pocket Exploration

Deep Pocket Exploration

By Ruth Williams | February 1, 2017

A modification to traditional docking software enables the examination of a ligand’s passage into its receptor.

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image: Infographic: Modeling Molecules’ Receptor Binding

Infographic: Modeling Molecules’ Receptor Binding

By Ruth Williams | February 1, 2017

A software upgrade follows ligands step-wise into their binding sites on receptors.

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