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Single-cell genome analyses reveal the amount of mutations a human brain cell will collect from its fetal beginnings until death.

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image: Captivated by Chromosomes

Captivated by Chromosomes

By | December 1, 2017

Peering through a microscope since age 14, Joseph Gall, now 89, still sees wonder at the other end.

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image: Passing the Torch

Passing the Torch

By | December 1, 2017

Looking back, looking forward

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The switch from maternal factors involves dynamic reprogramming of the zygotic genome.

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New technologies reveal the dynamic changes in mouse and human embryos during the first week after fertilization.

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Activating genes for reprogramming factors for a short time transforms large numbers of differentiated cells into multipotent forms that could be useful for cell-based therapies.

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image: Image of the Day: Skate Youngsters 

Image of the Day: Skate Youngsters 

By | November 28, 2017

Scientists study the development of scales in skate embryos. 

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image: New CAR T-Cell Therapy Shows Promise in Trial for Leukemia

New CAR T-Cell Therapy Shows Promise in Trial for Leukemia

By | November 21, 2017

The immunotherapy, which targets CD22 on cancer cells rather than CD19, might prove useful in patients for whom previous T-cell treatments were unsuccessful. 

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image: Child Receives Transgenic Skin Over Most of His Body

Child Receives Transgenic Skin Over Most of His Body

By | November 8, 2017

A combination gene-and-cell therapy has given a boy with a grievous skin disease a new lease on life, and has resolved a dermatology debate to boot.

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image: Image of the Day: Tadpole Prism

Image of the Day: Tadpole Prism

By | November 3, 2017

Scientists are making use of Xenopus tadpoles to study autism risk genes. 

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