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Activating genes for reprogramming factors for a short time transforms large numbers of differentiated cells into multipotent forms that could be useful for cell-based therapies.

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image: New CAR T-Cell Therapy Shows Promise in Trial for Leukemia

New CAR T-Cell Therapy Shows Promise in Trial for Leukemia

By | November 21, 2017

The immunotherapy, which targets CD22 on cancer cells rather than CD19, might prove useful in patients for whom previous T-cell treatments were unsuccessful. 

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image: Child Receives Transgenic Skin Over Most of His Body

Child Receives Transgenic Skin Over Most of His Body

By | November 8, 2017

A combination gene-and-cell therapy has given a boy with a grievous skin disease a new lease on life, and has resolved a dermatology debate to boot.

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image: FDA Approves Second CAR T-Cell Therapy

FDA Approves Second CAR T-Cell Therapy

By | October 19, 2017

The therapy, produced by Kite Pharma and owned by Gilead Sciences, is approved for use against some types of large B-cell lymphomas. 

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These engineered “cells” were made from the secretions and membranes of human mesenchymal stem cells.

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See researchers' recipe for synthetic mesenchymal stem cells, which showed cardiac regenerative potential in mice.

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Four products have already qualified for the regenerative medicine advanced therapy (RMAT) designation that provides extra interactions with the agency, and sooner.

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image: Cell Lines Gain Cancer-Related Mutations

Cell Lines Gain Cancer-Related Mutations

By | April 27, 2017

A screen of human embryonic stem cell lines finds several that accumulated changes in the gene TP53, including aberrations commonly seen in cancer.

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image: First Clinic-Ready Stem Cell Repository

First Clinic-Ready Stem Cell Repository

By | April 6, 2017

The UK Stem Cell Bank offers several lines derived from human embryonic tissue.

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image: Suicide Switch for Transplanted Stem Cells

Suicide Switch for Transplanted Stem Cells

By | March 2, 2017

Researchers use an inducible gene to limit tumor growth from human iPSCs transplanted into mice.

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