Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.

Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.

Self-contained synthetic E. coli resistant to viral infection could prove invaluable to the biotechnology industry by increasing product consistency and reducing safety concerns. 

if (n == null) The Scientist - Beyond the Fruit Fly The Scientist 9[18]:13, Sep. 18, 1995 Research Beyond the Fruit Fly By Karen Young Kreeger Of all the animal species described thus far by scientists, insects account for nearly five-sixths. Nearly 1 million are already identified, with taxonomists estimating another 1 million to go. Despite their ubiquity on Earth, the study of insects has only recently been married to the explosion of molecular biologic

Bacteria inhabit most tissues in the human body, and genes from some of these microbes have made their way to the human genome. Could this genetic transfer contribute to diseases such as cancer?

Credit: William Jacobs, Albert Einstein College of MedicineTuberculosis bacterium The battles that scientists wage against bacteria and viruses resemble chess matches between grandmasters and supercomputers. Highly intelligent people are pitted against entities that aren't conscious but that nevertheless hold two big advantages. Populated by hosts of individually sensitive microchips or microorganisms, these entities can react with lightning speed. And tutored intensively by computer programmers

Quieting immune attacks against pathogens and even providing nutrients to the invaders could improve health, according to a new line of research.

As much as rainforests or deep-sea vents, the human gut holds rich stores of microbial chemicals that should be mined for their pharmacological potential.

One warning came in black-and-white in 1993: A U.S. Congressional Office of Technology Assessment report projected that releasing 100 kilograms of aerosolized anthrax spores upwind of the U.S. capital could kill between 130,000 and 3 million people-a lethality at least matching that of a hydrogen bomb. Last year, a U.S. Justice Department exercise revealed that discharging pneumonic plague in Denver could create 3,700 or more cases, with an estimated 950 or more deaths within a week.1 Then, acco

Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.