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tag herpesvirus immunology neuroscience disease medicine culture

Amyloid plaques (stained for amyloid-? peptide) detected in a post-mortem brain sample of a patient with Alzheimer's disease. Purple purple dots in the background are the nuclei of neurons and glia.
Herpes Viruses Implicated in Alzheimer’s Disease
Anna Azvolinsky | Jun 21, 2018 | 5 min read

A new study shows that the brains of Alzheimer’s disease patients have a greater viral load, while another study in mice shows infection leads to amyloid-β build up.

herpes herpesvirus ms multiple sclerosis
Type of Herpes Virus Tied to Multiple Sclerosis
Katarina Zimmer | Jan 10, 2020 | 5 min read
A study of 16,000 people suggests that human herpesvirus 6A is a risk factor for developing multiple sclerosis, reinvigorating a neglected hypothesis that the virus could be involved in triggering the disease.
The Breakthrough Prize ?Trophy
2024 Breakthrough Prizes in Life Sciences
Danielle Gerhard, PhD | Sep 14, 2023 | 10 min read
This year’s Breakthrough Prizes honor advances in CAR T cancer therapies, cystic fibrosis, and Parkinson’s disease.
Rendering of a light blue NLRP3 inflammasome against a black background
Inflammation in Brain’s Immune Cells Triggers Depressive Behavior in Mice
Dan Robitzski | Nov 17, 2022 | 5 min read
In stressful conditions, specialized protein complexes in microglia induce neurotoxic activity in astrocytes that leads to the change in behavior.
Some Antibiotics Rev Up Host Immune Response to Viruses
Shawna Williams | Apr 9, 2018 | 4 min read
The antimicrobial drug neomycin protects mice from some viral infections, complicating the picture of the relationship between antibiotics and susceptibility to viruses.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Does Multiple Sclerosis Have a Herpesvirus Connection?
Douglas Steinberg | May 1, 2000 | 9 min read
Editor's Note: This is the second of two articles on the difficulties of proving that a virus contributes to a disease. The first article, on mouse mammary tumor virus and human breast cancer, appeared in the April 17 issue of The Scientist.1 Donald R. Carrigan and Konstance K. Knox Someone once said that if you want to ruin your reputation, go into MS [multiple sclerosis] research, quips Jacqueline E. Friedman, a senior research associate at Rockefeller University. But Friedman, who deals wit
3D image of a neuron cell network with a red glow representing inflammation.
New Insight into Brain Inflammation Inspires New Hope for Epilepsy Treatment 
Deanna MacNeil, PhD | Jun 1, 2023 | 2 min read
Clinicians and researchers teamed up to investigate how inappropriate proinflammatory mechanisms contribute to the pathogenesis of drug-refractory epilepsy.
Brain cell in purple on a black background. Arc mRNAs are labeled green and are mainly localized in the cell nucleus and in the dendrites.
Short-lived Molecules Support Long-term Memory 
Alejandra Manjarrez, PhD | Jun 6, 2023 | 3 min read
A gene essential for information storage in the brain engages an autoregulatory feedback loop to consolidate memory.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.

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