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tag rats culture neuroscience disease medicine

Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Neuroscience
The Scientist Staff | Jul 24, 1994 | 2 min read
P. Ernfors, J.-P. Merlio, H. Persson, "Cells expressing mRNA for neurotrophins and their receptors during embryonic rat development," European Journal of Neuroscience, 4:1140-58, 1992. Patrik Ernfors (Whitehead Institute for Biomedical Research, Cambridge, Mass.): "Previous studies by other researchers have shown that neurotrophins can prevent the cell death of partially overlapping, but also specific, sets of neurons in culture.
Neuroscience
The Scientist Staff | Jul 24, 1994 | 2 min read
P. Ernfors, J.-P. Merlio, H. Persson, "Cells expressing mRNA for neurotrophins and their receptors during embryonic rat development," European Journal of Neuroscience, 4:1140-58, 1992. Patrik Ernfors (Whitehead Institute for Biomedical Research, Cambridge, Mass.): "Previous studies by other researchers have shown that neurotrophins can prevent the cell death of partially overlapping, but also specific, sets of neurons in culture.
The Breakthrough Prize ?Trophy
2024 Breakthrough Prizes in Life Sciences
Danielle Gerhard, PhD | Sep 14, 2023 | 10 min read
This year’s Breakthrough Prizes honor advances in CAR T cancer therapies, cystic fibrosis, and Parkinson’s disease.
Infant hands holding bottle of milk on light blue floor background.
Myo-inositol in Human Breast Milk Improves Brain Connectivity
Charlene Lancaster, PhD | Oct 16, 2023 | 4 min read
Researchers find that the sugar myo-inositol is abundant early in lactation and increases synapse size and abundance in the developing brain.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
3D multicolored conceptual image representing hallucinogens and the human brain.
Natural High: Endogenous Psychedelics in the Gut and Brain
Iris Kulbatski, PhD | Sep 8, 2023 | 8 min read
Psychedelics are evolutionarily ancient compounds produced by fungi, plants, and microbes. Humans also synthesize psychedelics. Researchers want to know how and why.
Neurons (green) fire differently depending on whether the astrocytes (red) they are grown with are cultivated from people with or without fragile X.
Astrocytes Fuel Erratic Firing in Fragile X Neurons
Lauren Schenkman, Spectrum | May 30, 2023 | 4 min read
This new understanding could one day lead to targeted treatments. 
Brain cell in purple on a black background. Arc mRNAs are labeled green and are mainly localized in the cell nucleus and in the dendrites.
Short-lived Molecules Support Long-term Memory 
Alejandra Manjarrez, PhD | Jun 6, 2023 | 3 min read
A gene essential for information storage in the brain engages an autoregulatory feedback loop to consolidate memory.
A mutated cell with a spiky membrane
Mutations in Autism-Linked Gene Cause Membrane Mischief
Holly Barker, PhD, Spectrum | Jan 26, 2023 | 4 min read
Inactivating TAOK1 prompts tentacle-like protrusions to form all over a neuron’s surface, revealing the gene’s role in molding the membrane.

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