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tag extracellular matrix genetics genomics developmental biology

Bugs as Drugs to Boost Cancer Therapy
Danielle Gerhard, PhD | Jan 18, 2024 | 7 min read
Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.
Location, Location, Location
Anna Azvolinsky | Apr 1, 2017 | 9 min read
Since first proposing that a cell’s function and biology depend on its surroundings, Mina Bissell continues to probe the role of the extracellular matrix.
Advances in the functional characterization of newly discovered microproteins hint at their diverse roles  in health and disease
The Dark Matter of the Human Proteome
Annie Rathore | Apr 1, 2019 | 10 min read
Advances in the functional characterization of newly discovered microproteins hint at diverse roles in health and disease.
An image of lung tissue acquired using a MALDI imaging mass spectrometer.
Glycogen Metabolism May Play a Key Role in Pulmonary Fibrosis
Charlene Lancaster, PhD | Sep 11, 2023 | 4 min read
Researchers discover that glycogen and N-linked glycans accumulate in fibrotic regions of the lung and may be important for therapy development.
Microscopy image of the cnidarian <em>Hydractinia symbiolongicarpus&nbsp;</em>with cell nuclei stained blue and oocytes stained yellow
Ancient Immunoglobulin Genes Help Cnidarians Decide to Fight or Fuse
Sophie Fessl, PhD | Oct 11, 2022 | 4 min read
Immunoglobulin genes might have evolved much earlier than previously expected, perhaps even in the common ancestor of Cnidarians and Bilateria, a study suggests.
The Psychiatrist’s Jigsaw
Megan Scudellari | Nov 1, 2013 | 10+ min read
Researchers are piecing together the devilishly complex sets of genetic alterations underlying schizophrenia and bipolar disorder.
Conceptual image showing molecules making up a brain shape
The Noncoding Regulators of the Brain
Christie Wilcox, PhD | Sep 12, 2022 | 10+ min read
Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.
bacteria inside a biofilm
How Bacterial Communities Divvy up Duties
Holly Barker, PhD | Jun 1, 2023 | 10+ min read
Biofilms are home to millions of microbes, but disrupting their interactions could produce more effective antibiotics.
Recent Trials for Fragile X Syndrome Offer Hope
Randi Hagerman | Sep 1, 2019 | 10+ min read
Despite a solid understanding of the biological basis of fragile X syndrome, researchers have struggled to develop effective treatments.
Cancer cell
Interrogating the Complexities of the Tumor Microenvironment
Alison Halliday, PhD, Technology Networks | May 19, 2023 | 5 min read
Gaining a better understanding of the dynamic and reciprocal interactions between cancer cells and the tumor microenvironment is essential for improving patient diagnosis and treatment.

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