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tag viruses genetics genomics culture microbiology

bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Photograph from 1918 influenza pandemic shows mask-wearing women holding stretchers at backs of ambulances in Saint Louis, Missouri.
100-Year-Old Lungs Yield Genetic Samples of 1918 Flu Viruses
Christie Wilcox, PhD | May 18, 2021 | 2 min read
Influenza RNA sequences from three sets of lungs preserved in formalin since 1918 provide new insights into the deadly pandemic.
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
A micrograph from the first US case of COVID-19, with SARS-CoV-2 virus particles in blue
SARS-CoV-2 Can Spread Via Cell-to-Cell Transmission
Catherine Offord | Apr 4, 2022 | 2 min read
The virus’s ability to slip directly from one cell to another may help it avoid some of the body’s immune responses.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Scientists Clone SARS-CoV-2 Genome with Quick Yeast-Based Method
Ruth Williams | May 6, 2020 | 4 min read
The use of yeast artificial chromosomes has enabled the rapid genetic reconstruction of the novel coronavirus.
Metal shelves densely packed with preserved tissue specimens of various sizes, all suspended in glass containers.
Evolution of 1918 Flu Virus Traced from Century-Old Samples
Dan Robitzski | May 10, 2022 | 5 min read
The work reveals that the pandemic flu was likely the direct predecessor of the seasonal H1N1 flu that circulated for decades.
Artist&rsquo;s rendition of red SARS-CoV-2 coronaviruses floating near blue strands of DNA.
COVID-19 Infections May Reshape Genetic Landscape
Holly Barker, PhD | Mar 30, 2023 | 3 min read
SARS-CoV-2 infection triggers structural changes in the host cell’s DNA, which provide a molecular explanation for long COVID, a new study suggests. 
A scanning electron micrograph of the picozoan Picomonas judraskeda
Picozoans Are Algae After All: Study
Christie Wilcox, PhD | May 6, 2021 | 5 min read
Phylogenomics data place the enigmatic plankton in the middle of the algal family tree, despite their apparent lack of plastids—an organelle characteristic of all other algae.
Watercolor coronaviruses in green, red, blue, and purple are layered above an abstract background of watercolor swashes
Plenty of Evidence for Recombination in SARS-CoV-2
Abby Olena, PhD | Sep 2, 2021 | 7 min read
Different variants of the virus behind the COVID-19 pandemic are swapping chunks of genetic material, but it’s not yet clear what implications that may have for public health.

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