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tag inhibitory neurons disease medicine evolution neuroscience

Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Aging-Related Diseases May Be a Negative Outcome of Human Evolution
Sukanya Charuchandra | May 31, 2018 | 3 min read
Genetic adaptations for human brain development also make us vulnerable to Alzheimer’s disease, according to a new study.  
Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
Neuronal network with electrical activity of neuron cells in 3D
How Do Neurons Work?
Jennifer Zieba, PhD | Dec 15, 2022 | 6 min read
Neurons transmit sensory and mechanical information across synapses and along axons throughout the body via chemical signals and electrical impulses.
Brain cell in purple on a black background. Arc mRNAs are labeled green and are mainly localized in the cell nucleus and in the dendrites.
Short-lived Molecules Support Long-term Memory 
Alejandra Manjarrez, PhD | Jun 6, 2023 | 3 min read
A gene essential for information storage in the brain engages an autoregulatory feedback loop to consolidate memory.
illustration of brain cells in blue with amyloid plaques in orange and pink immune cells
Excerpt from The Memory Thief
Lauren Aguirre | Jun 1, 2021 | 10+ min read
Author Lauren Aguirre finds reasons for optimism in the fight against Alzheimer’s disease.
Conceptual image showing molecules making up a brain shape
The Noncoding Regulators of the Brain
Christie Wilcox, PhD | Sep 12, 2022 | 10+ min read
Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.
3D multicolored conceptual image representing hallucinogens and the human brain.
Natural High: Endogenous Psychedelics in the Gut and Brain
Iris Kulbatski, PhD | Sep 8, 2023 | 8 min read
Psychedelics are evolutionarily ancient compounds produced by fungi, plants, and microbes. Humans also synthesize psychedelics. Researchers want to know how and why.
Can Viruses in the Genome Cause Disease?
Katarina Zimmer | Jan 1, 2019 | 10+ min read
Clinical trials that target human endogenous retroviruses to treat multiple sclerosis, ALS, and other ailments are underway, but many questions remain about how these sequences may disrupt our biology.

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