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Capsule Reviews
Bob Grant | May 1, 2016 | 4 min read
Sorting the Beef from the Bull, Cheats and Deceits, A Sea of Glass, and Following the Wild Bees
The Genetics of Society
Claire Asher and Seirian Sumner | Jan 1, 2015 | 10 min read
Researchers aim to unravel the molecular mechanisms by which a single genotype gives rise to diverse castes in eusocial organisms.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
Surpassing the Law of Averages
Jeffrey M. Perkel | Sep 1, 2009 | 7 min read
By Jeffrey M. Perkel Surpassing the Law of Averages How to expose the behaviors of genes, RNA, proteins, and metabolites in single cells. By necessity or convenience, almost everything we know about biochemistry and molecular biology derives from bulk behavior: From gene regulation to Michaelis-Menten kinetics, we understand biology in terms of what the “average” cell in a population does. But, as Jonathan Weissman of the University of Califo
The Neurobiology of Rehabilitation
Ricki Lewis | Jun 29, 2003 | 10+ min read
Courtesy of Eric D. Laywell SPHERES OF PROMISE These neurospheres, clusters of cells in culture derived from the CNS of mice, are stained with antibodies against a neuronal protein (red), and a astrocyte protein (green). They have a nuclear counterstain (blue). The brain and spinal cord were once considered mitotic dead ends, a division of neurons dwindling with toddlerhood, with memory and learning the consequence of synaptic plasticity, not new neurons. But the discovery of neural stem
How to Create a Successful Fish Tale?
A. J. S. Rayl | Aug 19, 2001 | 10+ min read
More than 80 percent of the planet's living organisms exist only in aquatic ecosystems. Some may harbor secrets to human origins, and clues, treatments--perhaps even cures--for human disease. Some are critical bioindicators that portend the health of the biosphere. Yet, overall, scientists know little about the biochemical processes of these life forms. The vast, rich knowledge within the oceans and freshwater systems on Earth remains virtually untapped, because in the world of biological resear
Nature's Own Version of Superglue
Leslie Pray | Jun 23, 2002 | 5 min read
Volume 16 | Issue 13 | 24 | Jun. 24, 2002 Previous | Next Nature's Own Version of Superglue Understanding how insect feet adhere to slippery, wet surfaces has been a centuries-long quest | By Leslie Pray Image: Courtesy of Isle of Wight History Centre A close-up picture of the common fly. "The foot of a fly is a most admirable and curious contrivance, for by this the flies are enabled t
Forthcoming Books
The Scientist Staff | Nov 1, 1987 | 4 min read
ARCHAEOLOGY The Birth of Prehistoric Chronology: Dating Methods and Dating Systems In Nineteenth Century Scandinavian Archaeology. Bo Graslund. Cambridge University Press November, 150 pp, $39.50. Traces the origin and subsequent development of dating systems, examining how these systems grew and were improved and refined. BIOCHEMISTRY Biochemistry of Metabolism: Volume 11. David D. Davies, ed. Academic Press: November, 388 pp, $85. Discusses the metabolism of plants, emphasizing the b
Getting in Tune With the Enemy--Microbes
Joshua Lederberg | Jun 1, 2003 | 6 min read
Ned Shaw After a lapse of some decades, germs and disease have again been very much on our minds, largely because of the dreadful effect of AIDS throughout the world. We also have had a reawakened consciousness that globally prevalent diseases like tuberculosis and malaria remain historical scourges. Now the daily news tells us of new outbreaks such as severe acute pulmonary syndrome, or SARS, spreading from China, with an outcome that cannot be confidently predicted at this time. Throughout
Alternative Splicing Goes Mainstream
Sam Jaffe | Dec 14, 2003 | 10 min read
In eukaryotic genetics, the one-gene/one-protein concept has, for the most part, breathed its last. Researchers have rallied behind mechanisms such as alternative splicing, which may allow a lowly 30,000-gene genome to produce the dizzying variety of proteins that some believe is necessary to produce beings as complex as humans. Alternative splicing--the post-transcriptional editing process that can result in various mRNAs--was previously seen as an interesting but relatively uncommon sidesh

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