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tag nuclear pore genetics genomics microbiology

New insights reveal how herpesvirus infiltrates the nervous system.
Herpes Kidnaps Proteins to Take Up Residence in the Nervous System
Roni Dengler, PhD | Dec 6, 2021 | 3 min read
The herpes virus hitches a ride to the nuclei of neurons from a surprising source.
Alfred Pühler
Cormac Sheridan | Jan 12, 2009 | 3 min read
Alfred Pühler Forty years (and counting) at the forefront of microbiology research have not dimmed Pühler's infectious enthusiasm or voracious work ethic. By Cormac Sheridan Alfred Pühler has been a powerhouse in German microbiological research—initially in the area of plant-microbe interactions and later in industrial microbiology—over the past four decades. But he actually started out in nuclear physics, obtain
Researchers Blast Open Pathogen Genome
Barry Palevitz | Aug 18, 2002 | 6 min read
Image: Courtesy of Tim Elkins BRUTE FORCE: Remnant of an appressorium formed on Mylar. The appressorium produced a peg-like extension that penetrated the film, leaving a round hole. (Reprinted with permission, Annual Review of Microbiology, 50:491-512, 1996.) "The Lord shall smite thee with a consumption, and with a fever, and with an inflammation, and with an extreme burning, and with the sword, and with BLASTING, and with mildew; and they shall pursue thee until thou perish." Deuteronom
Bacteria Harbor Geometric “Organelles”
Amber Dance | Dec 1, 2018 | 10+ min read
Microbes, traditionally thought to lack organelles, get a metabolic boost from geometric compartments that act as cauldrons for chemical reactions. Bioengineers are eager to harness the compartments for their own purposes.
translation gene genetics ribosome enhancers knowable magazine
What Does It Look Like to “Turn On” a Gene?
Alla Katsnelson, Casey Rentz, and Knowable Magazine | May 3, 2019 | 8 min read
Only recently have scientists directly witnessed this most pivotal of events in biology, thanks to new technology that allows them to observe the process in living cells. It’s teaching them a lot.
Bioterrorism Research: New Money, New Anxieties
John Dudley Miller | Apr 6, 2003 | 8 min read
Ned Shaw US scientists have reason to feel both heady and scared. The federal government recently released unprecedented billions of dollars to fund bioterrorism research. Yet, the merits of this sudden shift in focus are being debated, and some worry that the money will be squandered or wasted. "I have been really very upset by the focus on bioterrorism," says Stanley Falkow, professor of microbiology and immunology and of medicine at Stanford University. "Everybody's talking about it, but th
Playing Up the Single Life
Amy Maxmen | Dec 1, 2010 | 7 min read
By Amy Maxmen Playing Up the Single Life Single-cell applications to help you explore the tiniest great unknown As researchers probe deeper into cell physiology, they are increasingly bumping into cells’ individual personalities. Identical genetic material and location, it seems, doesn’t prevent two cells from behaving differently, and in some cases this intercellular variation changes cell function and fate. Fluctuations within individual cells may
2019 Top 10 Innovations
The Scientist | Dec 1, 2019 | 10+ min read
From a mass photometer to improved breath biopsy probes, these new products are poised for scientific success.
The Shape of Heredity
Susan M. Gasser | Jul 1, 2009 | 10+ min read
By Susan M. Gasser The Shape of Heredity Tracking the dance of DNA and structural proteins within the nucleus shows that placement makes the difference between gene activity and silence. What's true of the best architecture is also true of cellular structures: form follows function. We biologists often take this mantra to an extreme, searching for the function of a molecule or gene without much consideration of its structure, its phys
Sons of Next Gen
Tia Ghose | Jun 1, 2012 | 8 min read
New innovations could bring tailored, fast, and cheap sequencing to the masses.

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