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tag adeno associated virus microbiology ecology neuroscience

Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
A needle drawing up fluid from an unlabeled vial.
Cancer Vaccination as a Promising New Treatment Against Tumors
Shelby Bradford, PhD | Mar 15, 2024 | 10+ min read
Vaccination has beaten back infections for more than a century. Now, it may be the next big step in battling cancer.
An Ocean of Viruses
Joshua S. Weitz and Steven W. Wilhelm | Jul 1, 2013 | 10+ min read
Viruses abound in the world’s oceans, yet researchers are only beginning to understand how they affect life and chemistry from the water’s surface to the sea floor.
Reprogrammed Müller Glia Restore Vision in Mice
Ashley Yeager | Aug 15, 2018 | 4 min read
A double gene-transfer therapy transformed the non-neuronal cells into rod photoreceptors in the retinas of animal models of congenital blindness.
Those We Lost in 2019
Ashley Yeager | Dec 30, 2019 | 6 min read
The scientific community said goodbye to Sydney Brenner, Paul Greengard, Patricia Bath, and a number of other leading researchers this year.
Articles Alert
Bernard Dixon | Mar 5, 1989 | 7 min read
LIFE SCIENCES BY BERNARD DIXON European Editorial Offices The Scientist Uxbrldge, U.K. " Positron emission tomography studies in 20 Swedish army officer cadets have revealed metabolic changes in the same regions of the brain during both tactile learning and tactile recognition. This exciting glimpse of brain metabolism accompanying conscious activity appears in a new journal launched by the European Neurosciences Association and designed to interest the entire universe of neuroscientists, fro
2020 Top 10 Innovations
The Scientist | Dec 1, 2020 | 10+ min read
From a rapid molecular test for COVID-19 to tools that can characterize the antibodies produced in the plasma of patients recovering from the disease, this year’s winners reflect the research community’s shared focus in a challenging year.
Letters
Ronald Paque | Oct 4, 1987 | 6 min read
As a disenfranchised victim of the peer-review system, I consider that the myriad proposals for modifying peer review are less than encouraging. In his letter “Can Peer Review Be Improved?” (May 4, 1987, P. 10), Moshe Wolman is more than correct when he points out the inhibitory effect peer review has on science. Innovative, creative ideas that depart from dogma are usually given unfundable priorities, especially when dealing with NIH. In 1985 NIH received more than 30,000 proposa
Frontlines
Hal Cohen | May 12, 2002 | 5 min read
CuresNow, a coalition of scientists, patient groups, and entertainment executives recently launched an ad campaign to rally opposition to the Brownback-Landrieu bill that would criminalize all forms of research cloning ("Popular ad couple Harry and Louise are back, opposing Bush cloning ban," Wall Street Journal, April 24, 2002). The characters were featured in commercials that helped sink Bill Clinton's health care reform plan. In the current effort, the fictitious Louise refers to a bill that

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