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tag adeno associated virus immunology neuroscience cell molecular biology evolution

Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
New Molecular Tools Enable Researchers To Correlate Viruses, Diseases
Karen Young Kreeger | Feb 4, 1996 | 7 min read
Viruses, Diseases Author: Karen Young Kreeger Sidebar: Professional Resources for Viral Disease Researchers In the mid- to late 1980s, numerous correlations were discovered between viruses and various types of cancers. For example, Epstein-Barr virus was associated with nasopharyngeal carcinoma and B-cell lymphoma, hepatitis B virus with liver cancer, and human papillomavirus with cervical cancer. Now, a decade later, basic and clinical scientists are finding out that viruses may also play a r
Defeating the Virus
Wayne C. Koff | May 1, 2015 | 10+ min read
Recent discoveries are spurring a renaissance in HIV vaccine research and development.
2020 Top 10 Innovations
The Scientist | Dec 1, 2020 | 10+ min read
From a rapid molecular test for COVID-19 to tools that can characterize the antibodies produced in the plasma of patients recovering from the disease, this year’s winners reflect the research community’s shared focus in a challenging year.
Creative Expression: Mammalian Expression Vectors and Systems
Christopher Smith | Feb 1, 1998 | 7 min read
Date: February 2, 1998 Chart 1 Chart 2 Prokaryotic expression systems, reviewed in the September 1, 1997, issue of The Scientist were part of the early repertoire of research tools in molecular biology. Although the expression of recombinant protein in prokaryotes provided a means to develop other research tools (antibodies, for example ) and study basic aspects of biological function, the scope and depth of this research were limited, especially with regard to eukaryotic proteins. The de novo
2018 Top 10 Innovations
The Scientist | Dec 1, 2018 | 10+ min read
Biology happens on many levels, from ecosystems to electron transport chains. These tools may help spur discoveries at all of life's scales.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
Optogenetic Therapies Move Closer to Clinical Use
Shawna Williams | Nov 16, 2017 | 6 min read
With a clinical trial underway to restore vision optogenetically, researchers also see promise in using the technique to treat deafness, pain, and other conditions.
Letters
Ronald Paque | Oct 4, 1987 | 6 min read
As a disenfranchised victim of the peer-review system, I consider that the myriad proposals for modifying peer review are less than encouraging. In his letter “Can Peer Review Be Improved?” (May 4, 1987, P. 10), Moshe Wolman is more than correct when he points out the inhibitory effect peer review has on science. Innovative, creative ideas that depart from dogma are usually given unfundable priorities, especially when dealing with NIH. In 1985 NIH received more than 30,000 proposa
Notebook
The Scientist Staff | Jul 7, 1996 | 7 min read
On June 14, a House Appropriations subcommittee gave some researchers cause for celebration when it surprisingly voted to remove a provision in a government spending bill that extended a ban on federal funding of human embryo research. However, their glee was short-lived. The full panel turned around on June 25 and adopted an amendment to continue the research ban. John Eppig, senior staff scientist at Jackson Laboratory in Bar Harbor, Maine, doubts that the ban will be overturned anytime soon,

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