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tag adeno associated virus genetics genomics neuroscience ecology disease medicine

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
2020 Top 10 Innovations
The Scientist | Dec 1, 2020 | 10+ min read
From a rapid molecular test for COVID-19 to tools that can characterize the antibodies produced in the plasma of patients recovering from the disease, this year’s winners reflect the research community’s shared focus in a challenging year.
Chemyx: Targeting Tissues with CRISPR Editing and Stereotaxic Techniques
Chemyx Inc. | Oct 26, 2017 | 3 min read
Using stereotaxic devices and syringe pumps to improve your CRISPR targeting
New ALS Therapies Move Closer to the Clinic
Jenny Rood | Sep 1, 2018 | 8 min read
After two decades of failure, novel scientific insights and technical progress are spurring meaningful innovation in the field.
The Infection Connection in Schizophrenia
Brendan Maher | Nov 2, 2003 | 7 min read
Adapted from image by I.I. Gottesman ©2001  GENES AND MORE: The risks of developing schizophrenia over a lifetime to the relatives of schizophrenia sufferers accord with a largely genetic explanation. Yet with 48% concordance for identical twins, environmental factors may play a role. It's a scary thought that one could develop a debilitating mental illness such as schizophrenia as easily as catching a cold. Well, it's more complicated than that, say advocates of the so-called infec
2018 Top 10 Innovations
The Scientist | Dec 1, 2018 | 10+ min read
Biology happens on many levels, from ecosystems to electron transport chains. These tools may help spur discoveries at all of life's scales.
Notebook
Steve Bunk | Nov 7, 1999 | 7 min read
Content Jumping DNA Semen pharming Screening for heart risk Real-time signaling PubSCIENCE starts, PubMedCentral grows When time stands still Shutting down the pump Brain gain JUMPING DNA Mutations aren't transmitted only by inheritance--they can cross species, too, according to recent findings by John F. McDonald, head of the genetics department at the University of Georgia (I.K. Jordan et al., "Evidence for the recent horizontal transfer of long terminal repeat retrotransposon," Proceedings of

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