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image: Glial Ties to Persistent Pain

Glial Ties to Persistent Pain

By | January 1, 2018

Immune-like cells in the central nervous system are now recognized as key participants in the creation and maintenance of persistent pain.

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image: Infographic: A Painful Pathway

Infographic: A Painful Pathway

By | January 1, 2018

Since the mid-2000s, the voltage-gated sodium channel NaV1.7 has emerged as a promising target for a new class of analgesics.

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image: Infographic: Two Pain Paths Diverge in the Body

Infographic: Two Pain Paths Diverge in the Body

By | January 1, 2018

The acute pain that results from injury or disease is very different from chronic pain.

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image: Targeting Sodium Channels for Pain Relief

Targeting Sodium Channels for Pain Relief

By | January 1, 2018

The race to develop analgesic drugs that inhibit sodium channel NaV1.7 is revealing a complex sensory role for the protein.

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image: New Resource Ranks Chemical Probes for Human Proteins

New Resource Ranks Chemical Probes for Human Proteins

By | December 14, 2017

With many probes being seriously flawed, Probe Miner helps researchers find those that are most specific and effective for manipulating their chosen proteins.

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Water bears can reanimate after years of desiccation—and gel-forming proteins unique to the animals may explain how.

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image: Image of the Day: Actin Burst

Image of the Day: Actin Burst

By | December 6, 2017

Researchers are looking at actin polymerization and calcium uptake in human cells to study mitochondrial division.

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image: Captivated by Chromosomes

Captivated by Chromosomes

By | December 1, 2017

Peering through a microscope since age 14, Joseph Gall, now 89, still sees wonder at the other end.

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image: In Situ Hybridization Explained

In Situ Hybridization Explained

By | December 1, 2017

Profilee Joseph Gall of the Carnegie Institute describes the process, which he developed in the 1960s.

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The Lawrence Berkeley National Laboratory researcher’s work will help predict how the Arctic is responding to climate change—and the global effects of those changes.

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