Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 

Genes activated in new environments include those used during development.

Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.

Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.

Researchers integrate scRNA-seq, spatial transcriptomics, and histology imaging data to show that spatial cellular architecture predicts glioblastoma prognosis.

With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.

This year’s Breakthrough Prizes honor advances in CAR T cancer therapies, cystic fibrosis, and Parkinson’s disease.

Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.

A high-quality genome sequence for this versatile insect will likely aid eco-evolutionary research.