Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.

Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.

The use of yeast artificial chromosomes has enabled the rapid genetic reconstruction of the novel coronavirus.

A green fluorescent dye with a novel DNA binding mechanism improves signal-to-noise in different DNA amplification assays.

Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.

Microbiome studies have yielded hundreds of ideas for ways to detect and influence human health, but the field struggles with reproducibility challenges that hamper bringing these goals to fruition. Identical tubes of fecal matter should help.

This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.

A high-quality genome sequence for this versatile insect will likely aid eco-evolutionary research.

With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.