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Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Researchers Blast Open Pathogen Genome
Barry Palevitz | Aug 18, 2002 | 6 min read
Image: Courtesy of Tim Elkins BRUTE FORCE: Remnant of an appressorium formed on Mylar. The appressorium produced a peg-like extension that penetrated the film, leaving a round hole. (Reprinted with permission, Annual Review of Microbiology, 50:491-512, 1996.) "The Lord shall smite thee with a consumption, and with a fever, and with an inflammation, and with an extreme burning, and with the sword, and with BLASTING, and with mildew; and they shall pursue thee until thou perish." Deuteronom
Epigenetics: Genome, Meet Your Environment
Leslie Pray | Jul 4, 2004 | 10+ min read
©Mehau Kulyk/Photo Researchers, IncToward the end of World War II, a German-imposed food embargo in western Holland – a densely populated area already suffering from scarce food supplies, ruined agricultural lands, and the onset of an unusually harsh winter – led to the death by starvation of some 30,000 people. Detailed birth records collected during that so-called Dutch Hunger Winter have provided scientists with useful data for analyzing the long-term health effects of prenat
2020 Top 10 Innovations
The Scientist | Dec 1, 2020 | 10+ min read
From a rapid molecular test for COVID-19 to tools that can characterize the antibodies produced in the plasma of patients recovering from the disease, this year’s winners reflect the research community’s shared focus in a challenging year.
Research Notes
Ricki Lewis | Apr 16, 2000 | 3 min read
Fly Model of Parkinson's Disease With genome projects finishing at an ever quickening pace, many new animal models of human disease are being developed. A very promising one is a Drosophila version of Parkinson's disease (M.B. Feany and W.B. Bender, "A Drosophila model of Parkinson's disease," Nature, 404:394-8, March 23, 2000). At Harvard Medical School, Mel Feany, an instructor in pathology, and Welcome Bender, a professor of biological chemistry and molecular pharmacology, created flies trans
Top 10 Innovations 2013
The Scientist | Dec 1, 2013 | 10+ min read
The Scientist’s annual competition uncovered a bonanza of interesting technologies that made their way onto the market and into labs this year.
Top Ten Innovations 2011
The Scientist | Jan 1, 2012 | 10+ min read
Our list of the best and brightest products that 2011 had to offer the life scientist
Those We Lost in 2018
Ashley Yeager | Dec 26, 2018 | 10+ min read
The scientific community said goodbye to a number of leading researchers this year.
Re-engineering Humans
The Scientist | Mar 1, 2007 | 10+ min read
We challenged experts across fields to imagine a new way to solve the problems of human aging. Our question: What if Humans were Designed to Last? By S. Jay Olshansky, Robert N. Butler, and Bruce A. Carnes Illustrations by Thom Graves When Michelangelo painted The Creation of Adam on the ceiling of the Sistine Chapel, he portrayed the Renaissance view of humanity as having been molded by the hand of its creator, a "perfect" physical spe
More Researchers Are 'Transitioning' Into Sales Careers
Ricki Lewis | Nov 13, 1994 | 7 min read
Dorothy Rodmann, a career-services consultant at the Washington, D.C.-based American Chemical Society (ACS), is seeing transitioning becoming a necessity for an increasing number of chemists. "In light of what has been happening in the job market -downsizing and strategic changes in direction [among chemical companies]--many chemists are looking at ways to move in different directions, and use their chemical knowledge and skills, of

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