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Finding DNA Tags in AAV Stacks
Finding DNA Tags in AAV Stacks
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening.
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening.
next generation sequencing
A Machine Learning Tool Uncloaks the Hidden Sources of Cancer Cells
Rachael Moeller Gorman | Oct 5, 2023 | 4 min read
Researchers created a model that uses clinical testing data to locate the primary site of cancer cells with no known origin, likely improving survival.
Poor Cancer Prognosis Associated with a Transcriptional Signature
Charlene Lancaster, PhD | Sep 11, 2023 | 4 min read
Researchers connect a tumor’s leading edge transcriptional profile to poor survival outcomes across cancer types.
Optimizing PCR: Proven Tips and Troubleshooting Tricks
Tanuka Biswas, PhD | 10 min read
Scientists optimize PCR to ensure successful amplification and analysis.
Redesigning Medicine Using Synthetic Biology
Alison Halliday, PhD, Technology Networks | Jun 21, 2023 | 5 min read
Drawing inspiration from nature, synthetic biology offers exciting opportunities to transform the future of medicine.
Interrogating the Complexities of the Tumor Microenvironment
Alison Halliday, PhD, Technology Networks | May 19, 2023 | 5 min read
Gaining a better understanding of the dynamic and reciprocal interactions between cancer cells and the tumor microenvironment is essential for improving patient diagnosis and treatment.
Tracking Community Health Through Wastewater Surveillance
Charlene Lancaster, PhD | 8 min read
By monitoring disease biomarkers within wastewater, researchers gain insight into disease prevalence within communities.
Unearthing Hidden Family Secrets: Tracing the Lineage of a Centuries-Old Grand-Mummy
Iris Kulbatski, PhD | Dec 13, 2022 | 3 min read
Researchers show how a toxic therapy helped identify a mummy using preserved DNA.
Uncovering Leprosy’s Genetic Recipe for Success
Nele Haelterman, PhD | Aug 17, 2022 | 3 min read
Researchers identify what makes certain people more likely to contract leprosy than others.
New Strategies to Discover Human Disease Genes
The Scientist | 2 min read
Learn how researchers across health-related fields identify and characterize disease-causing genomic variants.
Aquatic Bacteria Reveal a Common Genetic Link to a Deadly Human Pathogen
Iris Kulbatski, PhD | Mar 7, 2022 | 5 min read
Researchers use genetic clues to track the spread of antibiotic resistant bacteria from the environment to patients.
Gut Bugs May Help Centenarians Reach Their 100th Birthdays
Roni Dengler, PhD | Aug 30, 2021 | 3 min read
Centenarians have distinct microbiomes with species that produce unique bile acids, which may help thwart illness.
The Scientist's Journal Club: Transcriptomics
The Scientist | 2 min read
Scientists discuss their latest findings on immune cell dynamics, neurodegenerative disease risk factors, and rare cell types obtained from bulk and single cell RNA sequencing experiments.
Ancient Humans Had Hepatitis B
Abby Olena, PhD | May 9, 2018 | 4 min read
Analyses of more than 300 ancient human genomes show that Hepatitis B virus has infected humans for at least 4,500 years and has much older origins than modern viral genomes would suggest.
Q&A: Confirming Next-Gen Sequencing Results with Sanger
Tracy Vence | Oct 11, 2016 | 4 min read
Ambry Genetics CEO Aaron Elliott discusses his team’s recent analysis of 20,000 clinical next-generation sequencing panels.
How Can Core Labs Help You Get Started with NGS?
The Scientist | 1 min read
Next-generation sequencing (NGS) core facility scientists and researchers new to NGS discuss their fruitful collaborations, highlighting how to receive expert help from genomics facilities.
Spiders, Prey Leave DNA
Bob Grant | Nov 30, 2015 | 1 min read
A study of black widow spiders suggests that the arachnids leave traces of their own genetic material and DNA from prey in their sticky webs.
TS Live: Genetic Time Machine
Bob Grant | Jun 12, 2015 | 1 min read
Piecing together scraps of DNA from a 400,000-year-old hominin femur
Targeted DNA Sequencing: Probing for Answers
The Scientist and Roche | 1 min read
A more focused investigation for more in-depth answers.
What’s Old Is New Again
Bob Grant | Jun 1, 2015 | 10+ min read
Revolutionary new methods for extracting, purifying, and sequencing ever-more-ancient DNA have opened an unprecedented window into the history of life on Earth.