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tag polar research culture disease medicine ecology

bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
A microscopy image of an apical-out colon organoid that was produced using MilliporeSigma’s protocol.
Turning Organoids Inside Out 
The Scientist, MilliporeSigma, and Hub Organoids | Aug 15, 2023 | 4 min read
Discover how a new procedure reverses the polarity of typical basolateral-out organoids to form versatile apical-out organoids.
Exploring the Past, Present, and Future of Brain Organoids 
Niki Spahich, PhD | Feb 18, 2024 | 5 min read
Paola Arlotta seeks to understand the complex symphony of brain development in vitro by using organoid models.
Image of pancreatic organoids under a microscope with immunofluorescent staining
Pancreatic Organoids Take the Stage
Laura Tran, PhD | Dec 1, 2023 | 2 min read
Meritxell Huch tackled her pipedream of growing three-dimensional pancreatic tissue in a dish.
Polar Regions Offer Rich Opportunities For Research
Douglas Siegel-causey | Apr 26, 1998 | 7 min read
Polar science is receiving increased attention this spring with several new developments in the national and international arenas. At last month's meeting of the United States-Russian Joint Commission on Economics and Technological Cooperation, one of the major agenda items was Arctic sciences. This commission has met semiannually since it was initiated in 1993 by U.S. Vice President Al Gore and former Russian Prime Minister Viktor Chenomyrdin to establish new intergovernmental agreements for
The Ecology of Tumors
Paraic A. Kenny, Celeste M. Nelson, and Mina J. Bissell | Apr 1, 2006 | 10+ min read
FEATUREThe Ecology of Tumors   Courtesy of Nasa Ames Research CenterBy perturbing the microenvironment, wounds and infection may be key to tumor development.BY PARAIC A. KENNY, CELESTE M. NELSON, AND MINA J. BISSELLNo tumor is an island. Chemical and physical forces exerted by the diverse cellular populations that surround a tumor - its so-called microenvironment - shape development and progression. Manipulating these 'ecologi
Science with Borders: Researchers Navigate Red Tape
Max Kozlov | Mar 1, 2021 | 10 min read
Scientists who work with foreign biological specimens face a patchwork of permits that threaten to block their projects, with potentially harmful consequences for the ecosystems they study.
a newly hatched mosquito sits on top of water, with its discarded cocoon floating below
In Vitro Malaria Sporozoite Production May Lead to Cheaper Vaccines
Katherine Irving | Jan 20, 2023 | 4 min read
A method for culturing the infectious stage of the Plasmodium lifecycle could increase malaria vaccine production efficiency by tenfold, study authors say.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Patient-derived colon organoids from a healthy individual
Generating Mini-Guts for Drug Screening
The Scientist and MilliporeSigma | Dec 16, 2022 | 4 min read
Human gut organoids facilitate precise disease modeling and power high-throughput drug development efforts.

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