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Pembrolizumab combined with chemotherapy nearly doubles survival rates and shrinks tumors in some individuals.

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Genetic analyses uncover cellular hallmarks of bladder cancer tumors that don’t respond, but interfering with one of those characteristics in a mouse model causes tumors to shrink.  

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image: Human Brain Organoids Thrive in Mouse Brains

Human Brain Organoids Thrive in Mouse Brains

By Ashley Yeager | April 16, 2018

After implantation, the tissue developed blood vessels and became integrated into neuronal networks in the animals’ brains.

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A new microscopy program requires no fluorescent markers to identify cell type, nuclei, and other characteristics.

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image: New Ovarian Cancer Vaccine Shows Promise

New Ovarian Cancer Vaccine Shows Promise

By Catherine Offord | April 12, 2018

A preliminary clinical trial finds that the personalized therapy improves survival rates and has no severe side-effects.

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This is the first time the precise brain cells and their connections controlling a complex behavior have been worked out. 

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A proposed definition of the disease emphasizes signs of neurodegeneration and the presence of β-amyloid and tau, rather than cognitive symptoms.

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Researchers identified thousands of immature neurons in the brain region, countering a recent result showing little, if any, signs of neurogenesis.

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image: A Neuroscientist’s Journey Through Madness

A Neuroscientist’s Journey Through Madness

By Barbara Lipska with Elaine McArdle | April 1, 2018

After I was diagnosed with brain cancer and started to lose my mental health, the importance of my job came into clear focus.

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image: Cancer Evolutionist: A Profile of Charles Swanton

Cancer Evolutionist: A Profile of Charles Swanton

By Anna Azvolinsky | April 1, 2018

Motivated by his father’s cancer diagnosis, the Francis Crick Institute cancer geneticist has been revealing the ways tumors evolve and why they are so difficult to treat.

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