In rats, motherhood leaves long-term biological signatures in a brain region that is crucial for learning and memory.

Renewing the aging gut microbiome holds promise for preventing inflammatory brain and eye degeneration.

Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 

Beyond The Scientist’s coverage of COVID-19’s molecular underpinnings were many other stories highlighting the advances made in scientists’ understanding of the biology of cells.

A host lipid-modifying enzyme plays a key role in HIV envelope formation, viral maturation, and infectivity. 

With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.

A novel PET tracer targeting a receptor in myeloid cells can help monitor disease progression in a mouse model of multiple sclerosis.

Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.

Vaccination has beaten back infections for more than a century. Now, it may be the next big step in battling cancer.