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tag mitochondrial disease developmental biology genetics genomics ecology

bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
illustration of a mitochondrian inside a cell
Could Dad’s Mitochondrial DNA Benefit Hybrids?
Alejandra Manjarrez, PhD | Jan 20, 2022 | 7 min read
Studies have found that organisms can inherit mitochondria from male parents in rare instances, and both theoretical and experimental work hint that this biparental inheritance is more than just a fluke.
5 images related to stories highlighted in the article, including DNA strand, insect, and dog
Our Favorite Genetics Stories of 2021
Christie Wilcox, PhD | Dec 23, 2021 | 4 min read
Studies The Scientist covered this year illustrate the expanding importance of genetic and genomic research in all aspects of life science, from ecology to medicine.
Opinion: Too Many Mitochondrial Genome Papers
David R. Smith | Jun 29, 2015 | 3 min read
And too few insights gleaned from them
Advances in the functional characterization of newly discovered microproteins hint at their diverse roles  in health and disease
The Dark Matter of the Human Proteome
Annie Rathore | Apr 1, 2019 | 10 min read
Advances in the functional characterization of newly discovered microproteins hint at diverse roles in health and disease.
A tubifer cardinalfish
Genome Spotlight: Tubifer cardinalfish (Siphamia tubifer)
Christie Wilcox, PhD | Apr 28, 2022 | 3 min read
These tiny reef fish harbor luminous bacteria, and the chromosome-level assembly of the species’ genome may facilitate the duo’s use as a vertebrate model for symbiosis.
a black abalone on a rock
Genome Spotlight: Black Abalone (Haliotis cracherodii)
Christie Wilcox, PhD | Jun 23, 2022 | 3 min read
The researchers who constructed the first reference genome for this critically endangered mollusk say it will assist restoration efforts.
Illustration showing a puzzle piece of DNA being removed
Large Scientific Collaborations Aim to Complete Human Genome
Brianna Chrisman and Jordan Eizenga | Sep 1, 2022 | 10+ min read
Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.
Mitochondria Versus Nucleus
Juliet Ash | Feb 15, 2013 | 3 min read
Disruptions in the interaction between nuclear and mitochondrial DNA can lead to deficiencies in the mitochondrial energy-generating process, affecting fitness.
Nuclei swap to stop disease?
Jef Akst | Apr 13, 2010 | 3 min read
A technique may one day prevent something that is currently unpreventable -- the transmission of mitochondrial diseases from mother to child, according to a proof-of-concept paper published online today (April 14) in Nature. Blastocyst on day 5 after fertilizationImage: Wikimedia commons, EkemThe authors swapped the nuclei from one fertilized human egg with the nuclei from another, creating an embryo with nuclear DNA from the donor egg, but mitochondrial DNA primarily from the recipient. They s

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