p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.

This year’s Breakthrough Prizes honor advances in CAR T cancer therapies, cystic fibrosis, and Parkinson’s disease.

Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.

A reference sequence for this emerging model organism will facilitate research on type 2 diabetes and the health effects of circadian rhythm disruption.

An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.

The Sloan Kettering researcher used mutagenic screening to probe genes and molecular pathways, including Toll and Hedgehog, essential to development in fruit flies and mice.

The National Eye Institute (NEI) celebrates its 25th anniversary this year. But, as institute director Carl Kupfer notes, while its accomplishments over the years have more than justified its formation as a separate research agency of the National Institutes of Health, it took a bit of persuasion to carry out that vision. FAR-SIGHTED FOCUS: Cal Kupfer, the institute's first director, recounts NEI's past successes and looks forward to achieving new goals in treating eye disease. "In the 1950s,

The scientific community bid farewell to researchers who furthered the fields of molecular biology, virology, sleep science, and immunology, among others.

A look at some noteworthy scientists who died this year, leaving behind a legacy of research excellence.

With human research trials resulting in dozens of successful deliveries in the US and abroad, doctors move toward offering the surgery clinically, while working to learn all they can about uterine and transplant biology from the still-rare procedure.