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tag molecular clock genetics genomics microbiology

Individual bacterial transcriptomes each plotted as a single point create a ring-shaped structure.
Rapidly Dividing Bacteria Coordinate Gene Expression and Replication
Kamal Nahas, PhD | Mar 15, 2024 | 4 min read
E. coli divides faster than it can replicate its genome, while simultaneously expressing its genes. Scientists recently revealed the intricate molecular coordination that makes this possible.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Top 7 in Genomics & Genetics
Sabrina Richards | Sep 19, 2011 | 3 min read
A snapshot of the most highly ranked articles in genomics, genetics and related areas, from Faculty of 1000
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
bacteria inside a biofilm
How Bacterial Communities Divvy up Duties
Holly Barker, PhD | Jun 1, 2023 | 10+ min read
Biofilms are home to millions of microbes, but disrupting their interactions could produce more effective antibiotics.
Tagged for Cleansing
Michele Pagano | Jun 1, 2009 | 10+ min read
Tagged for Cleansing Not just the cell's trash and recycling center, the ubiquitin system controls complex cellular pathways with elegant simplicity and precision. By Michele Pagano have always gravitated toward order. I may even take it a bit too far according to friends who liken my office to a museum. However, I like to think it not a compulsion, but a Feng Shui approach to life. With this need for order, I may have been better suited to
Microbiology Vigil: Probing What's Out There
Jeffrey Perkel | May 4, 2003 | 9 min read
Courtesy of Mary Ann Moran  THE MICROBE HUNTER: University of Georgia graduate student Justine Lyons uses new molecular approaches to study the diversity of bacteria and fungi in a coastal salt marsh on Georgia's Sapelo Island. An outbreak of Salmonellosis erupted in Ohio, Michigan, Georgia, and Alabama during the winter of 1981. Frustrated epidemiologists could find no common link, until they finally realized what all the victims had in common: marijuana.1 Samples of pot used by some pa
Researchers Blast Open Pathogen Genome
Barry Palevitz | Aug 18, 2002 | 6 min read
Image: Courtesy of Tim Elkins BRUTE FORCE: Remnant of an appressorium formed on Mylar. The appressorium produced a peg-like extension that penetrated the film, leaving a round hole. (Reprinted with permission, Annual Review of Microbiology, 50:491-512, 1996.) "The Lord shall smite thee with a consumption, and with a fever, and with an inflammation, and with an extreme burning, and with the sword, and with BLASTING, and with mildew; and they shall pursue thee until thou perish." Deuteronom
DNA Software Takes The Drudgery Out Of Molecular Biology
Ricki Lewis | Sep 15, 1991 | 8 min read
Author: RICKI LEWIS, p.23 It is expected to take some 15 years to determine the sequence of the 3 billion base pairs that make up the human genome--roughly 550,000 base pairs per day. An analytical task of this magnitude would have been unthinkable just a few years ago, but today's rapidly advancing computer technology has made the international effort to sequence the human genome possible. C.B.S. Scientific Co. Inc. P.O. Box 856 Del Mar, Calif. 92014 Phone: (619) 755-4959 Fax: (619) 755-
Keeping Time with Drosophila
Laura Bonetta | Feb 3, 2002 | 10 min read
Circadian clocks—the biological timekeepers that operate on a daily cycle—keep virtually every living creature in tune with its environment. These internal clocks regulate a wide range of fundamental biological processes, including movement, smell, sleep, mating, and feeding. A true circadian clock is endogenous; that is, it keeps time even in the absence of external cues. The clock can, however, be reset, or entrained, by daylight, allowing the synchronization of circadian rhythms t

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