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tag human embryonic stem cells disease medicine genetics genomics microbiology

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
A bat flying in a dark cave
Turning on the Bat Signal
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
Patched-up human stem cells
Elie Dolgin | May 30, 2009 | 3 min read
For the first time, researchers have combined gene therapy and cellular reprogramming technologies in human cells to correct a genetic defect. After taking skin and hair cells from patients with a rare genetic disorder and fixing the aberrant mutation, the investigators successfully reprogrammed the cells to an embryonic-like state and then turned them into the very cell types that usually go awry, according to a linkurl:study;http://www.nature.com/nature/journal/vaop/ncurrent/abs/nature08129.ht
New Way to Make Embryonic Stem Cells
Amy Coombs | Oct 5, 2011 | 3 min read
A breakthrough in somatic cell nuclear transfer opens the possibility of producing human embryonic stem cells with a patient’s own genes.
Medical illustration depicting self-renewal of a single stem cell dividing into two identical cells.<br><br>
What Is Stemness and Pluripotency?
Deanna MacNeil, PhD | Sep 30, 2022 | 5 min read
Scientists study pluripotent stems cells to understand early development and how to use them in regenerative medicine, disease modeling, and drug discovery.
Illustration showing a puzzle piece of DNA being removed
Large Scientific Collaborations Aim to Complete Human Genome
Brianna Chrisman and Jordan Eizenga | Sep 1, 2022 | 10+ min read
Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.
Professor Alexandra Whiteley and graduate student Autumn Matthews look at an image of a western blot on their laboratory computer.
An Ancient Viral Protein May Play a Key Role in ALS
Aditi Subramaniam, PhD | Aug 15, 2023 | 4 min read
Researchers find that UBQLN2 gene dysfunction causes a virus-like protein to accumulate in cells, which changes gene expression and may contribute to disease progression in amyotrophic lateral sclerosis (ALS).
Julie Trolle and Jef Boeke
Self Sufficient Cells?
Katherine Irving | Jun 1, 2023 | 4 min read
Animal cells cannot produce 9 of the 20 amino acids they need to function. Some researchers are looking to change that.

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