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tag autoimmune disease immunology cell molecular biology culture disease medicine

3D illustration of damaged myelin sheath seen in demyelinating diseases such as multiple sclerosis.
Tracking Down Innate Immune Cells in Multiple Sclerosis
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 5 min read
A novel PET tracer targeting a receptor in myeloid cells can help monitor disease progression in a mouse model of multiple sclerosis.
A bat flying in a dark cave
Turning on the Bat Signal
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
Eat Yourself to Live: Autophagy’s Role in Health and Disease
Vikramjit Lahiri and Daniel J. Klionsky | Mar 1, 2018 | 10+ min read
New details of the molecular process by which our cells consume themselves point to therapeutic potential.
3D illustration of a tapeworm infestation in a human intestine
Return of the Worms
Catherine Offord | Dec 1, 2021 | 10+ min read
Immunologists and parasitologists are working to revive the idea that helminths, and more specifically the molecules they secrete, could help treat allergies and autoimmune disease.
Erika More developed a jello-like tissue system to study how immune cells stimulate tissues and blood vessel growth.
An Engineer’s Perspective on Autoimmunity
Aparna Nathan, PhD | Dec 10, 2021 | 4 min read
Erika Moore builds biomaterials to study disparate lupus outcomes.
Immunology
Eugene Russo | Mar 1, 1998 | 3 min read
Edited by: Eugene Russo T CELL STARTER: Harvard's Michael Grusby believes that research on Stat pathways will lead to a better understanding of T cell differentiation. M.H. Kaplan, U. Schindler, S.T. Smiley, M.J. Grusby, "Stat6 is required for mediating responses to IL-4 and for the development of Th2 cells," Immunity, 4:313-9, 1996. (Cited in more than 75 publications as of February 1998) Comments by Michael J. Grusby, Department of Immunology and Infectious Diseases, Harvard School of Public
Immunology
The Scientist Staff | Nov 22, 1998 | 4 min read
K.C. Garcia, M. Degano, R.L. Stanfield, A. Brunmark, M.R. Jackson, P.A. Peterson, L. Teyton, I.A. Wilson, "An alpha-ß T cell receptor structure at 2.5Å and its orientation in the TCR-MHC complex," Science, 274:209-19, 1996. (Cited in more than 240 papers since publication) Comments by Ian A. Wilson, professor of molecular biology at The Scripps Research Institute in La Jolla, Calif. D.N. Garboczi, P. Ghosh, U. Utz, Q.R. Fan, W.E. Biddison, D.C. Wiley, "Structure of the complex bet
Immunology: Highlights From A Hot Biological Field
Scott Veggeberg | Mar 21, 1993 | 6 min read
Some of the most influential papers in 1992, according to data provided by the Philadelphia-based Institute for Scientific Information, were in immunology. This is not surprising, given the field's applications in stemming AIDS, cancer, and other pressing diseases. The most cited paper published within the last two years is from the Max Planck Institute for Biology in Tbingen, Germany (K. Falk, et al., Nature, 351:290, 1991). This paper, which by the end of February 1993 had been referred to i
Autoimmunity
The Scientist Staff | May 25, 1997 | 3 min read
Edited by: Thomas W. Durso V.K. Kuchroo, M.P. Das, J.A. Brown, A.M. Ranger, S.S. Zamvil, R.A. Sobel, H.L. Weiner, N. Nabavi, L.H. Glimcher, "B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy," Cell, 80:707-18, 1995. (Cited in nearly 260 publications as of April 1997) GOOD AND BAD: Harvard's Laurie Glimcher received a surprise after injecting a pair of antibodies into mice suffering from experimental alle
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.

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