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image: Immune Checkpoint Found Lacking in Type 1 Diabetes

Immune Checkpoint Found Lacking in Type 1 Diabetes

By Ruth Williams | November 15, 2017

Boosting levels of a the immunosuppressive protein PD-L1 in blood stem cells halts diabetes in a mouse model of the disease.

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image: Immunotherapy Promising for Diabetes: Study

Immunotherapy Promising for Diabetes: Study

By Aggie Mika | August 9, 2017

A small clinical trial demonstrates that peptide immunotherapy can halt the progression of early-stage type 1 diabetes.

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image: Infographic: Immune Irritation in the Gut

Infographic: Immune Irritation in the Gut

By Catherine Offord | June 1, 2017

A look at how gluten affects patients with celiac disease

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image: The Celiac Surge

The Celiac Surge

By Catherine Offord | June 1, 2017

A rapid increase in the global incidence of the condition has researchers scrambling to understand the causes of the trend, and cope with the consequences.

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image: Image of the Day: Seizure-Inducing Worms

Image of the Day: Seizure-Inducing Worms

By The Scientist Staff | February 16, 2017

Onchocerca volvulus, a parasitic worm, may cause a fatal form of epilepsy in children by inducing an autoimmune reaction.

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Founder and CEO, Curable; Adjunct Assistant Professor, University of Pittsburgh. Age: 35

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image: Saving Jon

Saving Jon

By The Scientist Staff | October 1, 2016

Meet the researcher/entrepreneur who started a nonprofit that seeks to solve the science behind a rare disease that threatens the life of her younger brother.

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Three therapeutic doses administered during early life disturb the animals’ microbiomes and lead to enduring changes in the immune systems of non-obese diabetic mice, researchers report.

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image: Contributors

Contributors

By Catherine Offord | June 1, 2016

Meet some of the people featured in the June 2016 issue of The Scientist.

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image: Toward Targeted Therapies for Autoimmune Disorders

Toward Targeted Therapies for Autoimmune Disorders

By Lawrence Steinman | June 1, 2016

Training the immune system to cease fire on native tissues could improve outcomes for autoimmune patients, but clinical progress has been slow.

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