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tag stem cells evolution developmental biology cell molecular biology ecology

Stem cells for brain cancer
Peter B. Dirks | Apr 1, 2006 | 3 min read
FEATUREThe Ecology of Tumors Stem cells for brain cancer BY PETER B. DIRKSNeural stem cell biology took off in 1992 when Brent Reynolds and Samuel Weiss, working at the University of Calgary, discovered that culturing mammalian brain cells in serum-free conditions (in EGF and bFGF), yielded clonally derived colonies of undifferentiated neural cells (neurospheres). This culture system demonstrated that cells within these colonies showed cardinal pr
Guts and Glory
Anna Azvolinsky | Apr 1, 2016 | 9 min read
An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.
New beta cells without stem cells?
Kerry Grens | May 28, 2007 | 3 min read
Two studies find adult pancreatic cells maintain islet population, contradicting a hypothesis that regeneration relies on stem cells
Stem Cell Discoveries Stir Debate
Douglas Steinberg | Nov 12, 2000 | 9 min read
Editor's Note: This is the first of two articles on questions raised by recent stem cell discoveries. The second article, focusing on various organs and the nervous system, will appear in the Nov. 27 issue of The Scientist. Researchers first isolated embryonic stem cells (ESCs) from mouse blastocysts almost 20 years ago, and a paper announcing the discovery of human ESCs emerged in 1998. Adult-derived stem cells (ASCs) have since become the rage in certain quarters of biology, with unexpected--
Top Five Institutions in Biological Sciences Doctorate Programs
Karen Young Kreeger | Oct 15, 1995 | 2 min read
Programs Author: Karen Young Kreeger (Ranked by scores on a survey of scholarly quality of program faculty among peers. Scores on a scale of 0 to 5*") Rank Institution Score Biochemistry and Molecular Biology 1 University of California, San Francisco 4.84 2 Massachusetts Institute of Technology 4.83 Stanford University 4.83 3 University of California, Berkeley 4.81 4 Harvard University 4.80 5 Yale University 4.59 Cell and Developmental Biology 1 Massachusetts Institute of Technology 4.86 2 Ro
One Protein to Rule Them All
Shelby Bradford, PhD | Feb 28, 2024 | 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
Using Brain Organoids in Human Health and Disease Research
Using Brain Organoids in Human Health and Disease Research
The Scientist | Jan 17, 2024 | 1 min read
Learn how scientists across life science and engineering disciplines join forces to build brain organoids that mimic neurodevelopment.
On the left is a normally developing mouse embryo, on the right is a slightly larger mouse embryo that also contains horse cells that glow green.
Chimera research opens new doors to understanding and treating disease
Hannah Thomasy, PhD, Drug Discovery News | Aug 9, 2023 | 10 min read
Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.
The death of biology
Ishani Ganguli | Jul 1, 2006 | 2 min read
At Harvard, biology is an endangered species. Next fall's wide-eyed freshmen will have to head down the street to Massachusetts Institute of Technology if they want to concentrate (Harvard-speak for major) in the subject, because it will no longer be offered in Harvard Square. This change was puzzling to my editor, who concentrated in biology at Harvard, and to me, a 2005 graduate with a degree in biochemistry. So I consulted Robert Lue, my former advisor and cochair
How Groups of Cells Cooperate to Build Organs and Organisms
Michael Levin | Sep 1, 2020 | 10+ min read
Understanding biology’s software—the rules that enable great plasticity in how cell collectives generate reliable anatomies—is key to advancing tissue engineering and regenerative medicine.

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