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tag noncoding rna neuroscience developmental biology disease medicine

An artist's rendition of an RNA molecule in light blue on a dark blue background
Same RNA Acts in Neurodegeneration and Cancer
Abby Olena, PhD | Oct 29, 2021 | 3 min read
The long noncoding RNA MINCR, implicated in ALS and Alzheimer’s disease as well as several types of cancer, appears to function differently when present at high versus low levels.
Conceptual image showing molecules making up a brain shape
The Noncoding Regulators of the Brain
Christie Wilcox, PhD | Sep 12, 2022 | 10+ min read
Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.
Top 7 in developmental biology
Bob Grant | Dec 17, 2010 | 3 min read
A snapshot of the most highly ranked articles in developmental biology, from Faculty of 1000
Exploring the Past, Present, and Future of Brain Organoids 
Niki Spahich, PhD | Feb 18, 2024 | 5 min read
Paola Arlotta seeks to understand the complex symphony of brain development in vitro by using organoid models.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Kathryn Anderson, forward genetics, genetics & genomics, model organisms, Toll, hedgehog, embryogenesis, developmental biology, cell differentiation, cilia,
Developmental Biologist Kathryn Anderson Dies at 68
Amanda Heidt | Jan 6, 2021 | 4 min read
The Sloan Kettering researcher used mutagenic screening to probe genes and molecular pathways, including Toll and Hedgehog, essential to development in fruit flies and mice.
What Paraspeckles Can Teach Us About Basic Cell Biology
Archa Fox | Dec 1, 2019 | 10+ min read
Discovering a new type of subnuclear body taught me how pursuing the unexpected can lead to new insights—in this case, about long noncoding RNAs and liquid-liquid phase separation in cells.
The dark matter of disease
Hannah Waters | Apr 24, 2011 | 5 min read
Scientists are beginning to unravel how non-coding DNA works across long distances of the genome to influence disease
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Traces of Trauma in Sperm RNA
Jeffrey M. Perkel | Apr 13, 2014 | 3 min read
A mouse study shows that molecular remnants of early-life stress can be passed on to future generations.

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