gene therapy, neuroscience

An aqueduct connecting the brain to the ear may make gene therapy for hearing loss less invasive.

Gene therapy may be the first step toward curing a rare genetic epilepsy.

The FDA pauses the research program on a lentivirus-based treatment for a rare neurological condition after a patient developed a bone marrow disorder that could presage leukemia.

The results of an early trial in 31 brain cancer patients finds immune activity boosted in the tumor, and possibly longer survival.

A double gene-transfer therapy transformed the non-neuronal cells into rod photoreceptors in the retinas of animal models of congenital blindness.

Researchers use a combination of ultrasound waves, genetic engineering, and synthetic drugs to switch specific neurons on and off in mice.

Upping a gene’s expression in rat brains made them better learners and normalized the activity of hundreds of other genes to resemble the brains of younger animals.

Localization of two proteins important for inner ear hair cell function suggests they are part of the elusive mechanotransduction channel. 

Expressing a gene for a component of the inner ear’s hair cells treated a form of genetic deafness.

Was the Human Genome Project the key to a gold mine?