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Sequencing of a single gene can spot patients with a dangerous form of mycosis fungoides better than other prognostic tests.  

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Crowdfunding can power investigations into diseases that would otherwise receive little attention.

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image: Slow March Toward a Canavan Cure

Slow March Toward a Canavan Cure

By Ashley Yeager | May 1, 2018

Two decades after a successful crowdfunding campaign, some clinical trial patients have seen improvements—but there’s still no approved treatment for the disease.

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Though Calliope Joy’s disease is too far progressed to be treatable, her parents have helped other children with metachromatic leukodystrophy get access to an experimental therapy.

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image: Preterm Labor May Be Sparked by Fetal Immune Reaction

Preterm Labor May Be Sparked by Fetal Immune Reaction

By Ruth Williams | April 25, 2018

Immune cells targeting maternal antigens are abundant in the blood of premature infants, suggesting fetal intolerance of mom may instigate early labor.  

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image: Image of the Day: Immune Cell In Action

Image of the Day: Immune Cell In Action

By The Scientist Staff | April 23, 2018

By combining two new microscopy technologies, researchers filmed immune cells toiling away in the inner ear of a living zebrafish.

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Genetic analyses uncover cellular hallmarks of bladder cancer tumors that don’t respond, but interfering with one of those characteristics in a mouse model causes tumors to shrink.  

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image: New Ovarian Cancer Vaccine Shows Promise

New Ovarian Cancer Vaccine Shows Promise

By Catherine Offord | April 12, 2018

A preliminary clinical trial finds that the personalized therapy improves survival rates and has no severe side-effects.

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image: Some Antibiotics Rev Up Host Immune Response to Viruses

Some Antibiotics Rev Up Host Immune Response to Viruses

By Shawna Williams | April 9, 2018

The antimicrobial drug neomycin protects mice from some viral infections, complicating the picture of the relationship between antibiotics and susceptibility to viruses.

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image: Opinion: We Have Been Naive About Naive T Cells

Opinion: We Have Been Naive About Naive T Cells

By Theo van den Broek, José A.M. Borghans, and Femke van Wijk | April 6, 2018

Human naive T cells are far more heterogeneous than has long been appreciated, having implications for vaccine strategies.

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