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tag protein engineering immunology microbiology ecology evolution

bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
A needle drawing up fluid from an unlabeled vial.
Cancer Vaccination as a Promising New Treatment Against Tumors
Shelby Bradford, PhD | Mar 15, 2024 | 10+ min read
Vaccination has beaten back infections for more than a century. Now, it may be the next big step in battling cancer.
Bugs as Drugs to Boost Cancer Therapy
Danielle Gerhard, PhD | Jan 18, 2024 | 7 min read
Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.
T regulatory cell in red sandwiching an antigen presenting cell in blue
Gut Bacteria Help T Cells Heal Muscle: Study
Natalia Mesa, PhD | Mar 14, 2023 | 4 min read
Regulatory T cells in the colon travel to muscles to promote wound healing in mice, raising questions about how antibiotics may impact injury recovery.
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
a veterinarian in a white hazmat suit holding a small pig
The Long Journey to Resolve the Origins of a Previous Pandemic
Martha Nelson | Sep 2, 2021 | 10+ min read
Dozens of researchers, including myself, worked for years to uncover that swine flu had leapt to humans from a pig in Mexico in 2009. We learned a lot about influenza evolution, pig farming, and outbreak risk along the way.
Illustration of a targeted virus over a world map
The Hunt for a Pandemic’s Origins
Martha Nelson | Jan 4, 2022 | 10+ min read
Dozens of researchers, including myself, worked for years to uncover that swine flu had leapt to humans from a pig in Mexico in 2009. We learned a lot about influenza evolution, pig farming, and outbreak risk along the way.
Settlement Signal
Abby Olena, PhD | Jan 9, 2014 | 3 min read
A marine bacterium generates contractile structures that are essential for the metamorphosis of a tubeworm.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Mining Bacterial Small Molecules
L. Caetano M. Antunes, Julian E. Davies and B. Brett Finlay | Jan 1, 2011 | 10 min read
As much as rainforests or deep-sea vents, the human gut holds rich stores of microbial chemicals that should be mined for their pharmacological potential.

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