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Mary Jeanne Kreek, heroin, addiction, methadone, drug addiction, The Rockefeller University,
Mary Jeanne Kreek, Methadone Developer, Dies at 84
A physician and neurobiologist at the Rockefeller University who specialized in addiction research, Kreek was best known for her work on developing the treatment for heroin addiction.
Mary Jeanne Kreek, Methadone Developer, Dies at 84
Mary Jeanne Kreek, Methadone Developer, Dies at 84

A physician and neurobiologist at the Rockefeller University who specialized in addiction research, Kreek was best known for her work on developing the treatment for heroin addiction.

A physician and neurobiologist at the Rockefeller University who specialized in addiction research, Kreek was best known for her work on developing the treatment for heroin addiction.

disease & medicine, neuroscience, cell & molecular biology

early-life stress, histone, chromatin, epigenetics, epigenetic modification, methylation, DNA, protein, stress, adversity, mice, genetics, genomics
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Asher Jones | Mar 18, 2021 | 5 min read
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
Did Contaminated Water Exacerbate Brazilian Babies’ Zika Symptoms?
Ashley Yeager | Jun 1, 2020 | 4 min read
Elevated levels of a neurotoxin in northeastern Brazil’s drinking water and a high incidence of microcephaly in the region led scientists to look for a link, and they found one.
Lost Smell and Taste Hint COVID-19 Can Target the Nervous System
Ashley Yeager | Mar 24, 2020 | 5 min read
The symptoms suggest SARS-CoV-2 might infect neurons, raising questions about whether there could be effects on the brain that play a role in patients’ deaths, but the data are preliminary.
Inadequate Myelination of Neurons Tied to Autism: Study
Lisa Winter | Feb 4, 2020 | 2 min read
A mouse model of autism and postmortem brains of autistic individuals showed a lack of mature oligodendrocytes and less myelination than controls.
The Scientist Infographics: Editor’s Picks of 2019
Jef Akst | Dec 18, 2019 | 3 min read
This year’s most beautiful illustrations covered topics including the molecular underpinnings of Parkinson’s disease and strategies for tracking marine organisms around the world’s oceans.
Sergiu Pasca Builds Brains to Study Developmental Disease
Emily Makowski | Dec 1, 2019 | 3 min read
The Stanford University professor helped develop a technique to grow brain organoids from induced pluripotent stem cells.
Air Pollution May Damage People’s Brains
Catherine Offord | Oct 1, 2019 | 10+ min read
Contaminants in the atmosphere appear to have harmful effects on neurodevelopment and cognitive function.
Infographic: Is Cellular Waste at the Root of Parkinson’s Disease?
Ashley Yeager | Oct 1, 2019 | 1 min read
Damage to the lysosome, the organelle that removes excess proteins, lipids, and other materials, might be at the root of the disease.
Aggressive Cancers Feed Off the Brain’s Nerves
Emily Makowski | Sep 20, 2019 | 2 min read
Three studies show that tumor cells can behave like neurons.
human macrophage
Image of the Day: Alzheimer’s Genes
Nicoletta Lanese | Aug 19, 2019 | 1 min read
Mutations within the MS4A gene cluster have been linked to changes in protein levels that affect disease risk.
schwann cells
Special Schwann Cells in Mice Play Unsung Role in Pain
Nicoletta Lanese | Aug 16, 2019 | 2 min read
The glia seem to make up part of a newly described sensory organ, the discoverers suggest.
cardiac heart catheter ablation atrial fibrillation s100b
A Common Atrial Fibrillation Procedure Is Aided by Damaging Neurons
Emma Yasinski | May 24, 2019 | 4 min read
Patients in a study of catheter ablation who showed signs of more injury to nerve cells and glia in the heart had fewer symptoms after the treatment.
Neural Cell Types Tied to Autism Identified in Single-Cell Study
Ruth Williams | May 16, 2019 | 3 min read
An RNA analysis of human brain cells reveals gene expression changes in cortical neurons and microglia linked to autism spectrum disorder (ASD).
Circulation and Cell Function Revived in Dead Pigs’ Brains
Chia-Yi Hou | Apr 17, 2019 | 3 min read
Researchers develop a system to deliver synthetic blood to isolated brains hours after death.
Chemogenetics Method Uses Anti-Smoking Drug to Control Cells
Ruth Williams | Mar 14, 2019 | 3 min read
A new set of engineered receptors responds to an FDA-approved drug to provide the most potent chemogenetic toolkit to date.
Prenatal Exposure to Cannabis Affects the Developing Brain
Andrew Scheyer | Jan 1, 2019 | 10+ min read
Children born to moms who smoked or ingested marijuana during pregnancy suffer higher rates of depression, hyperactivity, and inattention.
The Scientist’s Most Stunning Infographics of 2018
Jef Akst | Dec 21, 2018 | 2 min read
From cellular self-digestion to the effects of exercise on the brain, our features editor picks her favorite art custom-made for the magazine.
How K2 and Other Synthetic Cannabinoids Got Their Start in the Lab
Ashley Yeager | Nov 27, 2018 | 7 min read
Originally intended for basic neuroscience research, the drugs were ultimately hijacked for illicit recreational use.
When Normal Touch Becomes Painful, the Same Neurons Are Involved
Ruth Williams | Oct 10, 2018 | 4 min read
In a condition called mechanical allodynia, when everyday activities exact misery, the same neurons that ordinarily transmit normal touch are involved in feelings of pain.
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