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Salmonella Injection Helps the Mouse Immune System Kill Tumors
Salmonella Injection Helps the Mouse Immune System Kill Tumors
Nanoparticle-coated bacteria can capture tumor antigens and deliver them to immune cells, triggering a response that improved survival rates in mice.
Nanoparticle-coated bacteria can capture tumor antigens and deliver them to immune cells, triggering a response that improved survival rates in mice.
cancer immunotherapy, microbiology
Infographic: Salmonella Shuttle Tumor Antigens to Immune Cells
Dan Robitzski | May 16, 2022 | 1 min read
Nanoparticle-coated bacteria carry cancer-derived proteins to dendritic cells, enabling the immune system to launch a response in a mouse model.
Tetanus Immunity Protects Mice Against Pancreatic Cancer
Amanda Heidt | Mar 24, 2022 | 3 min read
Because most people are vaccinated against tetanus as children, delivering benign bacteria carrying a tetanus antigen into pancreatic tumors makes them visible to memory cells in the immune system, researchers report.
Fecal Transplant Could Boost Immunotherapy to Treat Melanoma
Shawna Williams | Feb 12, 2021 | 4 min read
The results from two Phase 1 trials bolster the case that the gut microbiome plays a role in response to the drugs.
Does the Microbiome Help the Body Fight Cancer?
Catherine Offord | Jul 10, 2019 | 4 min read
Research in mice and humans is beginning to establish a link between the composition of microbes in the gut and immune responses to tumor cells, but the mechanisms are not yet clear.
Fecal Transplant Heals Colitis Caused by Immunotherapy
Anna Azvolinsky | Nov 12, 2018 | 4 min read
A case study of two patients with advanced cancer shows it might be possible to avoid a common and severe side effect of immunotherapy treatment.
Microbes Meet Cancer
Kate Yandell | Apr 1, 2016 | 10+ min read
Understanding cancer’s relationship with the human microbiome could transform immune-modulating therapies.
Immune Influence
Kate Yandell | Mar 31, 2016 | 1 min read
In recent years, research has demonstrated that microbes living in and on the mammalian body can affect cancer risk, as well as responses to cancer treatment.