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Researchers use the technique to turn on Oct4 or Sox2 in mouse embryonic fibroblasts and convert them into pluripotent cells. 

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image: Learning Opens the Genome

Learning Opens the Genome

By Ruth Williams | January 17, 2018

Researchers map learning-induced chromatin alterations in mouse brain cells, and find that many affect autism-associated genes.

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image: High-Throughput Epigenetics Analyses

High-Throughput Epigenetics Analyses

By Jyoti Madhusoodanan | January 1, 2018

Emerging technologies help researchers draw mechanistic links between metabolism and epigenetic modification of DNA.

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After an initial wounding, genes needed for repair remain ready for action.

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The switch from maternal factors involves dynamic reprogramming of the zygotic genome.

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New technologies reveal the dynamic changes in mouse and human embryos during the first week after fertilization.

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image: Contributors

Contributors

By Jef Akst and Bob Grant | November 1, 2017

Meet some of the people featured in the November 2017 issue of The Scientist.

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image: Advancing Techniques Reveal the Brain’s Impressive Diversity

Advancing Techniques Reveal the Brain’s Impressive Diversity

By Sara B. Linker, Tracy A. Bedrosian, and Fred H. Gage | November 1, 2017

No two neurons are alike. What does that mean for brain function?

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image: Scientists Look to Epigenetics to Thwart Viruses

Scientists Look to Epigenetics to Thwart Viruses

By Shawna Williams | September 1, 2017

Some viral pathogens modify chromatin and other epigenetic machinery, making them appealing drug targets.

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image: Contributors

Contributors

By Catherine Offord and Jef Akst | September 1, 2017

Meet some of the people featured in the September 2017 issue of The Scientist.

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