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tag zinc finger nuclease ecology disease medicine

Gene Editing Treats Mitochondrial Disorders in Mice
Catherine Offord | Sep 25, 2018 | 2 min read
Researchers used TALENs and zinc finger nucleases to correct disease-causing mutations.
First In Vivo Human Genome Editing to Be Tested in New Clinical Trial
Abby Olena, PhD | May 18, 2017 | 4 min read
Sangamo Therapeutics will use zinc finger nucleases to introduce the gene for a missing clotting factor into the livers of men with hemophilia B.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Gene Editing Treats Blood Disease
Annie Gottlieb | Jun 27, 2011 | 3 min read
Revising a dysfunctional gene in vivo for the first time, researchers successfully restore blood clotting in hemophiliac mice.
Illustration of DNA
Can “Gene Writing” Deliver What Gene Editing Can’t?
Dan Robitzski | Dec 12, 2022 | 10+ min read
A biotech startup called Tessera Therapeutics has made a splash with its claims about the trademarked technology. Is the excitement justified?
Researchers Engineer Epigenome Editors to Study How Gene Expression Affects Disease
Ashley Yeager | Jan 1, 2019 | 7 min read
Using CRISPR and other tools, scientists are modifying DNA methylation, histone marks, and other modifiers of gene expression to understand how they affect health and disease.
Updated Nov 17
First Patient Receives In Vivo CRISPR Editing
Jef Akst | Mar 4, 2020 | 3 min read
Doctors in Oregon delivered the gene editing machinery behind the retina in hopes of treating an inherited form of blindness, according to the companies that developed the therapy.
Using CRISPR to Edit Genes in Induced Pluripotent Stem Cells
Kelly Rae Chi | Sep 1, 2016 | 8 min read
Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.
Gene Editing: From Roots to Riches
Amanda B. Keener | Oct 1, 2016 | 5 min read
Advances in genetic manipulation have simplified the once daunting task of rewriting a gene.
labtools march 2019 the scientist dna
The Challenge of Using CRISPR to Knock In Genes
Anna Nowogrodzki | Mar 1, 2019 | 7 min read
Researchers are developing an array of techniques for accurately and efficiently inserting genes into DNA.

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