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tag genome wide association study microbiology disease medicine ecology

Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
Cartoon of the gut with different colored bacteria and a magnifying glass hovering over part of the gut.
Humans Rely on Gut Bacteria for an Enzyme that Prevents Jaundice
Kamal Nahas, PhD | Feb 16, 2024 | 5 min read
An absence of bilirubin-producing gut microbes may predispose individuals to some diseases, including inflammatory bowel disease.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Illustration of bacteriophages infecting a bacterium
Phages Treat Gut Inflammation in Mice
Andy Carstens | Aug 4, 2022 | 5 min read
Mixtures of viruses that attack inflammatory bowel disease–causing bacteria in mice also survive the digestive tract and are well-tolerated in humans, a study finds.
The cholera genome: an advance for science or for medicine?
Robert Walgate | Aug 7, 2000 | 6 min read
genome sequence will help in developing protection against the disease. Robert Walgate discovers that it might - but perhaps not in the most obvious ways.
Illustration showing a puzzle piece of DNA being removed
Large Scientific Collaborations Aim to Complete Human Genome
Brianna Chrisman and Jordan Eizenga | Sep 1, 2022 | 10+ min read
Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.
Microscope image of A549-ACE2 lung cells coinfected with SARS-CoV-2 and a reporter vector containing a key regulatory variant of interest in the region on human chromosome 3
How Genes from Neanderthals Predispose People to Severe COVID-19
Alakananda Dasgupta | Feb 22, 2023 | 4 min read
Researchers dissect the Neanderthal-derived region on chromosome 3 that drives severe COVID-19 to zero in on the key causal variants.
Are Phages Overlooked Mediators of Health and Disease?
Catherine Offord | Feb 1, 2021 | 10+ min read
Bacteria-infecting viruses affect the composition and behavior of microbes in the mammalian gut—and perhaps influence human biology.
Scientists Clone SARS-CoV-2 Genome with Quick Yeast-Based Method
Ruth Williams | May 6, 2020 | 4 min read
The use of yeast artificial chromosomes has enabled the rapid genetic reconstruction of the novel coronavirus.
Weathering Hantavirus: Ecological Monitoring Provides Predictive Model
Steve Bunk | Jul 4, 1999 | 7 min read
Photo: Steve Bunk Dave Tinnin, field research associate in the University of New Mexico's biology department, takes blood samples and measurements of rodents caught on the research station grounds. At the end of a freeway exit near Soccoro, N.M., the hairpin turn onto a gravel road is marked by a sign that warns, "Wrong Way." But it isn't the wrong way if you want to reach the University of New Mexico's (UNM) long-term ecological research (LTER) station. The sign's subterfuge is the first indi

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