nutshell, genetics & genomics

It’s not clear whether, or how, the organisms might play a role in disease pathology.

Government documents suggest that Chinese authorities continue to use Thermo Fisher supplies in mass collection of DNA from minority groups.

Guthrie established foundational concepts in the field of pre-mRNA splicing during her career at the University of California, San Francisco.

The findings mean that penguins may struggle to adapt under rapid climate change, researchers say.

Research finds that a dog’s behavior has little to do with its genes.

Analyzing the whole genome sequences of more than 18,000 tumors, researchers catalog nearly 60 new patterns of mutations that could inform cancer treatment.

Caskey’s contributions to the field were instrumental to modern genetics.

A new study links a variant of the apolipoprotein E gene called APOE ε4 to better memory in older age, even in the presence of amyloid plaques—a possible explanation for the variant’s persistence despite its association with an increased risk of Alzheimer’s disease.

Researchers found the relatively high proportion of DNA from a hominin cousin—nearly 5 percent—when they scanned more than 1,000 genomes from 118 distinct ethnic groups.

The FDA pauses the research program on a lentivirus-based treatment for a rare neurological condition after a patient developed a bone marrow disorder that could presage leukemia.

Massive extrachromosomal elements named after the hive-minded cyborg villains in Star Trek may be the first of their kind.

In a preprint, researchers fill in some of the holes left in the first draft of the human genetic code, published at the turn of the century.

Data from three studies indicate that fully vaccinated patients are able to stave off severe disease from the B.1.1.7, B.1.351, and P.1 variants.

After years of push back, the first batch of Oxitec’s engineered mosquitoes, designed to reduce population numbers, have been released in the Keys.

While some experts speculate the variant could be partially responsible for India’s current surge in SARS-CoV-2 infections, information about the effects of its mutations is only beginning to emerge.

The embryos completed one-third of their total gestation outside of a uterus.

Genetic analyses suggest that the virus came from a patient who survived the 2013–2016 West African outbreak.

Clinical trials were halted after the treatment’s vector that ferries in the healthy genetic sequence was identified in the genome of a patient’s cancer cells.

Instead, the full report will be available in mid-March.