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tag drug safety disease medicine neuroscience developmental biology microbiology

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Gut Molecule Linked to Decreased Myelination in Mouse Brains
Angie Voyles Askham, Spectrum | Feb 17, 2022 | 4 min read
A study shows that a molecule produced by intestinal microbes can enter the brain and that its presence is also associated with altered brain connectivity.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Infectious Diseases Expert To Head National AIDS Unit
The Scientist Staff | Sep 17, 1989 | 5 min read
The National Institute of Allergy and Infectious Diseases has named George W. Counts as head of the newly established Clinical Research Management Branch in the Treatment Research Program of NIAID’s Division of AIDS. Prior to the appointment, Counts, 54, had been a professor of medicine at the University of Washington, Seattle, since 1975. He also served as director of the Clinical Microbiology Laboratory at the Fred Hutchinson Cancer Research Center in Seat- tle from 1985 to 1989. Co
The Role of Mom’s Microbes During Pregnancy
Carolyn A. Thomson and Kathy D. McCoy | Aug 1, 2021 | 10+ min read
Bacteria in the gut influence the production of antibodies and themselves secrete metabolites. In a pregnant woman, these compounds may influence immune development of her fetus.
Monoclonal Antibodies Find Utility In Cell Biology
Ricki Lewis | Dec 11, 1994 | 10+ min read
But, just as antibodies are finding increasing utility in cell biology, a new Food and Drug Administration classification for those products with clinical utility may affect researchers' access to the important technology (see accompanying story). Monoclonal History MAbs were born in 1975, when Georges Kohler and Cesar Milstein at the Medical Research Council Laboratories in Cambridge, England, fused two types of cells to form a hy
Monoclonal Antibodies Find Utility In Cell Biology
Ricki Lewis | Dec 11, 1994 | 10+ min read
But, just as antibodies are finding increasing utility in cell biology, a new Food and Drug Administration classification for those products with clinical utility may affect researchers' access to the important technology (see accompanying story). Monoclonal History MAbs were born in 1975, when Georges Kohler and Cesar Milstein at the Medical Research Council Laboratories in Cambridge, England, fused two types of cells to form a hy
Those We Lost in 2019
Ashley Yeager | Dec 30, 2019 | 6 min read
The scientific community said goodbye to Sydney Brenner, Paul Greengard, Patricia Bath, and a number of other leading researchers this year.
How Orphan Drugs Became a Highly Profitable Industry
Diana Kwon | May 1, 2018 | 10+ min read
Government incentives, advances in technology, and an army of patient advocates have spun a successful market—but abuses of the system and exorbitant prices could cause a backlash.
Prenatal Exposure to Cannabis Affects the Developing Brain
Andrew Scheyer | Jan 1, 2019 | 10+ min read
Children born to moms who smoked or ingested marijuana during pregnancy suffer higher rates of depression, hyperactivity, and inattention.
2020 Top 10 Innovations
The Scientist | Dec 1, 2020 | 10+ min read
From a rapid molecular test for COVID-19 to tools that can characterize the antibodies produced in the plasma of patients recovering from the disease, this year’s winners reflect the research community’s shared focus in a challenging year.

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