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tag embryonic stem cells evolution culture

A person moving the hands of a vintage clock backwards.
Synthetic Circuits Reveal the Key to Rewinding the Cellular Clock
Charlene Lancaster, PhD | Mar 12, 2024 | 4 min read
Using a circuit-based system, scientists determined the ideal transcription factor levels to promote the successful reprogramming of fibroblasts into induced pluripotent stem cells.
Eyes grown from stem cells
Jef Akst | Apr 5, 2011 | 3 min read
Cultured mouse embryonic stem cells self-organize into a complex retinal structure
One Protein to Rule Them All
Shelby Bradford, PhD | Feb 28, 2024 | 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
Week in Review: February 23–27
Tracy Vence | Feb 27, 2015 | 3 min read
Stem cells in culture; engineered cancer biomarkers; small molecule improves stem cell homing; reproducible bacterial evolution; how human adaptive immunity develops
Artist’s rendition of a blue-green DNA double helix, viewed lengthwise from within one end.
Stem Cell Lines Riddled With Undetected Mutations
Dan Robitzski | Aug 12, 2022 | 4 min read
Most of the human induced pluripotent stem cells stored at major cell line repositories and used in research harbor thousands of DNA errors, a study finds, highlighting the need for improved quality control measures.
Julie Trolle and Jef Boeke
Self Sufficient Cells?
Katherine Irving | Jun 1, 2023 | 4 min read
Animal cells cannot produce 9 of the 20 amino acids they need to function. Some researchers are looking to change that.
3d rendered medically accurate illustration of a human embryo anatomy
The Ephemeral Life of the Placenta
Danielle Gerhard, PhD | Dec 4, 2023 | 10+ min read
Recent advances in modeling the human placenta, the least understood organ, may inform placental disorders like preeclampsia.
Multiple purple and pink renditions of stem cells appear as spherical clusters enveloped in translucent bubbles
Mammalian Embryos Might Not Need Primitive Streaks After All
Dan Robitzski | Dec 2, 2021 | 7 min read
The primitive streak, a structure that emerges during mammalian and avian gastrulation, might be a byproduct rather than a landmark of the embryonic development process.
Making Things Grow: Insect Cells, Stem Cells, and Primary Cell Lines All Pose Challenges for Cell Culturists
Laura Defrancesco | Jun 21, 1998 | 5 min read
Date: June 22, 1998 Insect Cell Culture Media, Suppliers of Primary Cell Culture Media Advantages for Protein Expression Studies Since the mid-1950s cultures of insects--cockroaches, fruit flies, and leafhoppers, to name a few--have been the object of quiet study by physiologists and cell biologists. But along came genetic engineering and suddenly insect cultures have been put in the spotlight since they provide advantages over both bacterial and mammalian systems for recombinant protein prod
Cell Lines Gain Cancer-Related Mutations
Kerry Grens | Apr 27, 2017 | 1 min read
A screen of human embryonic stem cell lines finds several that accumulated changes in the gene TP53, including aberrations commonly seen in cancer.

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