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tag artificial selection cell molecular biology immunology developmental biology microbiology

Guts and Glory
Anna Azvolinsky | Apr 1, 2016 | 9 min read
An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.
The AIDS Research Evaluators
Lynn Gambale | Jul 9, 1995 | 6 min read
Chairman: Arnold Levine, chairman, department of molecular biology, Princeton University Barry Bloom, Weinstock Professor and Howard Hughes Medical Institute (HHMI) investigator, department of microbiology and immunology, Albert Einstein College of Medicine, New York Rebecca Buckley, professor of pediatrics and immunology, Duke University Medical Center Charles Carpenter, chairman, Office of AIDS Research Advisory Committee; professor of medicine,Brown University School of Medicine Don
Illustration showing the upper part of a human body connected to a DNA helix
Unraveling the Mystery of Zombie Genes
Iris Kulbatski, PhD | Oct 31, 2023 | 6 min read
Digging into how and why some genes are resurrected after death sounds morbid, but it has practical applications. 
Maximize In Vitro Culture Possibilities
Linda Raab | Oct 25, 1998 | 4 min read
From Redmond, et al., "Perfused transcapillary smooth muscle and endothelial cell co-culture--a novel in vitro model," In Vitro Cellular & Developmental Biology--Animal, Volume 31:601-609. Copyright 1995 by the Society for In Vitro Biology. Reproduced with permission of the copyright owner. The Cellmax™ culture system uses hollow fiber bioreactor technology in applications as diverse as secreted protein production, lymphocyte expansion, and cellular co-cultivation. The concept of
Surpassing the Law of Averages
Jeffrey M. Perkel | Sep 1, 2009 | 7 min read
By Jeffrey M. Perkel Surpassing the Law of Averages How to expose the behaviors of genes, RNA, proteins, and metabolites in single cells. By necessity or convenience, almost everything we know about biochemistry and molecular biology derives from bulk behavior: From gene regulation to Michaelis-Menten kinetics, we understand biology in terms of what the “average” cell in a population does. But, as Jonathan Weissman of the University of Califo
Why So Soon?
Bob Grant | May 1, 2013 | 10+ min read
Researchers are using modern experimental tools to probe the mysterious molecular pathways that lead to premature labor and birth.
Stem Cell Discoveries Stir Debate
Douglas Steinberg | Nov 12, 2000 | 9 min read
Editor's Note: This is the first of two articles on questions raised by recent stem cell discoveries. The second article, focusing on various organs and the nervous system, will appear in the Nov. 27 issue of The Scientist. Researchers first isolated embryonic stem cells (ESCs) from mouse blastocysts almost 20 years ago, and a paper announcing the discovery of human ESCs emerged in 1998. Adult-derived stem cells (ASCs) have since become the rage in certain quarters of biology, with unexpected--
Frontlines
David Bradley | Nov 24, 2002 | 6 min read
Frontlines Image: Erica P. Johnson Artificial cell signaling Cells rely on chemical signals triggered by external change to keep them informed. Christopher Hunter, Nick Williams, and colleagues at Sheffield University, England, tested the cells' abilities against a chemical system that transmits information signals into an artificial cell without a single molecule passing through the membrane (P. Barton et al., "Transmembrane signaling," Angewandte Chemie International Edition, 41:3878-81,
Bacteria Harbor Geometric “Organelles”
Amber Dance | Dec 1, 2018 | 10+ min read
Microbes, traditionally thought to lack organelles, get a metabolic boost from geometric compartments that act as cauldrons for chemical reactions. Bioengineers are eager to harness the compartments for their own purposes.
2020 Top 10 Innovations
The Scientist | Dec 1, 2020 | 10+ min read
From a rapid molecular test for COVID-19 to tools that can characterize the antibodies produced in the plasma of patients recovering from the disease, this year’s winners reflect the research community’s shared focus in a challenging year.

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