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tag metabolism genetics genomics evolution microbiology

bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
a trio of infant mice, two brown mice on the ends and one white mouse in the middle
Mice Pass Epigenetic Tweaks to Pups
Katherine Irving | Feb 17, 2023 | 5 min read
An engineered methylation pattern persisted for four generations of mice, demonstrating transgenerational epigenetic inheritance can occur in mammals.
Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
A scanning electron micrograph of the picozoan Picomonas judraskeda
Picozoans Are Algae After All: Study
Christie Wilcox, PhD | May 6, 2021 | 5 min read
Phylogenomics data place the enigmatic plankton in the middle of the algal family tree, despite their apparent lack of plastids—an organelle characteristic of all other algae.
A Nile rat sitting atop fruits
Genome Spotlight: Nile Rat (Avicanthis niloticus)
Christie Wilcox, PhD | Nov 23, 2022 | 4 min read
A reference sequence for this emerging model organism will facilitate research on type 2 diabetes and the health effects of circadian rhythm disruption.
green algae, phytoplankton, giant virus, genetics & genomics, endogenization, evolution, diversity, eukaryote
Giant Viruses Can Integrate into the Genomes of Their Hosts
Amanda Heidt | Nov 19, 2020 | 4 min read
Rather than introducing small chunks of DNA as other viruses do, some giant viruses can contribute more than 1 million base pairs to a host’s genome, broadening the ways in which viruses may shape eukaryote evolution.
Photo of Monir Moniruzzaman
Monir Moniruzzaman Studies the Secrets of Giant Viruses
James M. Gaines | Jan 2, 2023 | 4 min read
The University of Miami researcher studies how a mysterious group of supersized viruses infects and influences the evolution of their hosts.
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
Fish in a big blue aquarium
Microbes Responsible for Stealing Aquarium Medicine
Amanda Heidt | Feb 1, 2022 | 6 min read
Researchers discover that bacteria break down medicinal compounds for their nitrogen, solving a mystery that has vexed aquatic veterinarians for years.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.

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