With just a molecular nudge, aggregates of embryonic stem cells take shape as a “gastroloid,” bearing the genetic hallmarks and spatial organization of early development.
Doctors implant custom-made organs, built from a tissue sample and a biodegradable scaffold, into four female patients born with underdeveloped or missing vaginas.
Once believed to be irrevocably differentiated, mature cells are now proving to be flexible, able to switch identities with relatively simple manipulation.
Fueled by her love of visual data and addicted to chromosomes, Abby Dernburg continues to study how homologous chromosomes find each other during gamete formation.