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image: A Systematic Approach to Finding Unannotated Proteins

A Systematic Approach to Finding Unannotated Proteins

By Katarina Zimmer | March 1, 2018

A study suggests that there is more to the eukaryotic genome than was previously suspected.


image: How Gaining and Losing Weight Affects the Body

How Gaining and Losing Weight Affects the Body

By Abby Olena | January 17, 2018

Millions of measurements from 23 people who consumed extra calories every day for a month reveal changes in proteins, metabolites, and gut microbiota that accompany shifts in body mass.

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Single-cell analyses from mouse samples detail the changes in cell distribution during infections.


Combined transcription and genome data from multiple tissues in hundreds of human donors reveal links between genotype and gene expression across the body.

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image: Live Cell Extractions

Live Cell Extractions

By Ruth Williams | October 1, 2017

Nanostraws that collect specimens from cells without killing them allow for repeated sampling.

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image: Sex Reversal Mystery Explained?

Sex Reversal Mystery Explained?

By Jef Akst | June 15, 2017

A proposed mechanism for how bearded dragons with male chromosomes hatch as females at high temperatures


Adding RNA sequencing analysis to genomic sequencing helps scientists uncover mutations likely responsible for genetic disorders they might otherwise miss.


image: Massively Parallel Perturbations

Massively Parallel Perturbations

By Ruth Williams | March 1, 2017

Scientists combine CRISPR gene editing with single-cell sequencing for genotype-phenotype screens.


image: Infographic: Single-Cell CRISPR Screens

Infographic: Single-Cell CRISPR Screens

By Ruth Williams | March 1, 2017

See how two new methods track responses to unique genetic manipulations in numerous individual cells in parallel.


Researchers solve the mystery of 15-year-old mutant ferns with disrupted sex determination.


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